User profiles for "author:Hua-Guo Xu"

HUA-GUO XU

Nanjing medical university
Verified email at njmu.edu.cn
Cited by 1446

Prevalence and burden of hepatitis D virus infection in the global population: a systematic review and meta-analysis

HY Chen, DT Shen, DZ Ji, PC Han, WM Zhang, JF Ma… - Gut, 2019 - gut.bmj.com
Objective Hepatitis D virus (HDV) is a defective virus that completes its life cycle only with
hepatitis B virus (HBV). The HBV with HDV super-infection has been considered as one of …

[HTML][HTML] Hepatitis D: challenges in the estimation of true prevalence and laboratory diagnosis

LY Chen, XY Pang, H Goyal, RX Yang, HG Xu - Gut Pathogens, 2021 - Springer
Hepatitis delta virus (HDV) is a defective single negative chain RNA virus, as its envelope
protein synthesis is dependent on hepatitis B virus (HBV). Studies have consistently shown …

Global prevalence of occult hepatitis B: A systematic review and meta‐analysis

DZ Ji, XY Pang, DT Shen, SN Liu… - Journal of Viral …, 2022 - Wiley Online Library
The study aimed to investigate the prevalence and risk factors associated with occult
hepatitis B virus (HBV) infection (OBI) in the global population. We searched PubMed …

MIR106B and MIR93 prevent removal of bacteria from epithelial cells by disrupting ATG16L1-mediated autophagy

C Lu, J Chen, HG Xu, X Zhou, Q He, YL Li, G Jiang… - Gastroenterology, 2014 - Elsevier
Background & Aims Variants in genes that regulate autophagy have been associated with
Crohn's disease (CD). Defects in autophagy-mediated removal of pathogenic microbes …

[HTML][HTML] Diagnostic utility of non-invasive tests for inflammatory bowel disease: an umbrella review

JT Shi, Y Zhang, Y She, H Goyal, ZQ Wu… - Frontiers in Medicine, 2022 - frontiersin.org
Background: To consolidate evidence from published systematic review and meta-analyses
evaluating the diagnostic performances of noninvasive tests for inflammatory bowel disease …

Association of rotavirus vaccines with reduction in rotavirus gastroenteritis in children younger than 5 years: a systematic review and meta-analysis of randomized …

ZW Sun, Y Fu, HL Lu, RX Yang, H Goyal… - JAMA …, 2021 - jamanetwork.com
Importance Rotavirus vaccines have been introduced worldwide, and the clinical
association of different rotavirus vaccines with reduction in rotavirus gastroenteritis (RVGE) …

[HTML][HTML] STING and liver disease

C Chen, RX Yang, HG Xu - Journal of Gastroenterology, 2021 - Springer
STING (stimulator of interferon genes) also known as transmembrane protein 173
(TMEM173) is a cytoplasmic DNA sensor which can be activated by the upstream cyclic …

LKB1 reduces ROS-mediated cell damage via activation of p38

HG Xu, YX Zhai, J Chen, Y Lu, JW Wang, CS Quan… - Oncogene, 2015 - nature.com
Abstract Liver kinase B1 (LKB1, also known as serine/threonine kinase 11, STK11) is a
tumor suppressor mutated in Peutz–Jeghers syndrome and in a variety of sporadic cancers …

[HTML][HTML] Diagnostic accuracy of fecal calprotectin for predicting relapse in inflammatory bowel disease: a meta-analysis

JT Shi, N Chen, J Xu, H Goyal, ZQ Wu… - Journal of Clinical …, 2023 - mdpi.com
Fecal calprotectin (FC) levels correlate with the disease activity of inflammatory bowel
diseases (IBD); however, the utility of FC in predicting IBD relapse remains to be …

Clinical utility of procalcitonin and its association with pathogenic microorganisms

HG Xu, M Tian, SY Pan - Critical Reviews in Clinical Laboratory …, 2022 - Taylor & Francis
In this review, we summarize the relationship of PCT with pathogens, evaluate the clinical
utility of PCT in the diagnosis of clinical diseases, condition monitoring and evaluation, and …