Background: It is not widely appreciated that nonsteroidal anti-inflammatory drugs (NSAIDs)
may cause damage distal to the duodenum. We reviewed the adverse effects of NSAIDs on …

The noninvasive assessment of intestinal permeability in humans has a 20-year history.
Because the tests are increasingly used in clinical practice and research and because there …

Nonsteroidal anti-inflammatory drugs (NSAIDs) can damage the gastrointestinal tract,
causing widespread morbidity and mortality. Although mechanisms of damage involve the …

BACKGROUND AND AIMS Assessing the presence and degree of intestinal inflammation
objectively, simply, and reliably is a significant problem in gastroenterology. We assessed …

In contrast with normal subjects where IgA is the main immunoglobulin in the intestine,
patients with active inflammatory bowel disease (IBD) produce high concentrations of IgG …

Background & Aims: Prediction of relapse of inflammatory bowel disease has important
implications for therapeutic stategies. We assessed whether measurement of intestinal …

BACKGROUND: Reduced bone mineral density in patients with inflammatory bowel disease
is thought to be due to disturbances in calcium homeostasis or the effects of corticosteroid …

Background & Aims: Differentiating symptoms of irritable bowel syndrome (IBS) from those of
organic intestinal disease is a familiar problem for physicians. The aim of this study was to …

Background & Aims: Conventional acidic nonsteroidal anti-inflammatory drugs frequently
cause small bowel inflammation. Diagnosis is largely based on assay of surrogate markers …

Background & Aims: Nonsteroidal anti-inflammatory drug (NSAID) gastropathy is sufficiently
important as to warrant co-administration of misoprostol or proton pump inhibitors or a switch …