Risk of hepatitis B virus (HBV) reactivation in hepatitis B surface antigen negative/hepatitis B core antibody positive patients receiving rituximab-containing …
The use of rituximab has been associated with increased risk of hepatitis B virus (HBV)
reactivation in patients who are hepatitis B surface antigen (HBsAg) negative and …
reactivation in patients who are hepatitis B surface antigen (HBsAg) negative and …
[HTML][HTML] Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time
S Chia, JL Low, X Zhang, XL Kwang, FT Chong… - Nature …, 2017 - nature.com
Genomics-driven cancer therapeutics has gained prominence in personalized cancer
treatment. However, its utility in indications lacking biomarker-driven treatment strategies …
treatment. However, its utility in indications lacking biomarker-driven treatment strategies …
Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination
R Sundar, DHW Liu, GGA Hutchins, HL Slaney… - Gut, 2021 - gut.bmj.com
Objective Endoscopic mucosal biopsies of primary gastric cancers (GCs) are used to guide
diagnosis, biomarker testing and treatment. Spatial intratumoural heterogeneity (ITH) may …
diagnosis, biomarker testing and treatment. Spatial intratumoural heterogeneity (ITH) may …
Identification and functional validation of caldesmon as a potential gastric cancer metastasis-associated protein
Q Hou, HT Tan, KH Lim, TK Lim, A Khoo… - Journal of proteome …, 2013 - ACS Publications
In this study, we aim to identify biomarkers for gastric cancer metastasis using a quantitative
proteomics approach. The proteins extracted from a panel of 4 gastric cancer cell lines, two …
proteomics approach. The proteins extracted from a panel of 4 gastric cancer cell lines, two …
Breast cancer in women with neurofibromatosis type 1 (NF1): a comprehensive case series with molecular insights into its aggressive phenotype
Purpose The purpose of the study was to improve the understanding of NF1-associated
breast cancer, given the increased risk of breast cancer in this tumour predisposition …
breast cancer, given the increased risk of breast cancer in this tumour predisposition …
Effect of concomitant statin, metformin, or aspirin on rituximab treatment for diffuse large B-cell lymphoma
Several pre-clinical studies report that statins interfere with the surface binding of rituximab
to CD20. This study investigated the effects of statins in patients with diffuse large B-cell …
to CD20. This study investigated the effects of statins in patients with diffuse large B-cell …
Preoperative prognostic factors after liver resection for non‐colorectal, non‐neuroendocrine liver metastases and validation of the Adam score in an Asian population
Background Historically, the benefit of liver resection for non‐colorectal, non‐
neuroendocrine (NCNN) liver metastases has been controversial. This study aims to …
neuroendocrine (NCNN) liver metastases has been controversial. This study aims to …
Individualized molecular profiling for allocation to clinical trials Singapore study—An Asian tertiary cancer center experience
PURPOSE Precision oncology has transformed the management of advanced cancers
through implementation of advanced molecular profiling technologies to identify increasingly …
through implementation of advanced molecular profiling technologies to identify increasingly …
Safety and efficacy of aflibercept in combination with fluorouracil, leucovorin and irinotecan in the treatment of Asian patients with metastatic colorectal cancer
DQ Chong, M Manalo, M Imperial, P Teo… - Asia‐Pacific Journal …, 2016 - Wiley Online Library
Aim To evaluate the safety and efficacy of the combination therapy of fluorouracil, leucovorin
and irinotecan (FOLFIRI) and aflibercept in Asian patients with metastatic colorectal cancer …
and irinotecan (FOLFIRI) and aflibercept in Asian patients with metastatic colorectal cancer …
[HTML][HTML] “Anti-HBc alone” in human immunodeficiency virus-positive and immuno-suppressed lymphoma patients
Hepatitis B virus (HBV) infection is endemic in various parts of the world. A proportion of
patients have resolved prior exposure to HBV, as evidenced by the clearance of circulating …
patients have resolved prior exposure to HBV, as evidenced by the clearance of circulating …