Background Metformin is a widely used first-line drug for treatment of type 2 diabetes.
Despite its advantages, metformin has variable therapeutic effects, contraindications, and …

The human microbiome has emerged as a central research topic in human biology and
biomedicine. Current microbiome studies generate high-throughput omics data across …

Background The study was conducted to investigate the effects of metformin treatment on
the human gut microbiome's taxonomic and functional profile in the Latvian population, and …

Metformin is the first-line pharmacotherapy for managing type 2 diabetes (T2D). However,
many patients with T2D do not respond to or tolerate metformin well. Currently, there are no …

Effects of metformin, the first-line drug for type 2 diabetes therapy, on gut microbiome
composition in type 2 diabetes have been described in various studies both in human …

Background Metformin is a widely prescribed antihyperglycemic agent that has been also
associated with multiple therapeutic effects in various diseases, including several types of …

Metformin, a biguanide agent, is the first-line treatment for type 2 diabetes mellitus due to its
glucose-lowering effect. Despite its wide application in the treatment of multiple health …

Metformin is a commonly used antihyperglycaemic agent for the treatment of type 2 diabetes
mellitus. Nevertheless, the exact mechanisms of action, underlying the various therapeutic …

Background Type 2 diabetes complications cause a serious emotional and economical
burden to patients and healthcare systems globally. Management of both acute and chronic …

The gut microbiome plays a pivotal role in the modulation of host responses during viral
infections, and recent studies have underscored its significance in the context of coronavirus …