[HTML][HTML] Surgical data science–from concepts toward clinical translation

L Maier-Hein, M Eisenmann, D Sarikaya, K März… - Medical image …, 2022 - Elsevier
Recent developments in data science in general and machine learning in particular have
transformed the way experts envision the future of surgery. Surgical Data Science (SDS) is a …

Minimally invasive versus open esophagectomy: meta-analysis of outcomes

G Sgourakis, I Gockel, A Radtke, TJ Musholt… - Digestive diseases and …, 2010 - Springer
Background A meta-analysis of the current literature was performed to compare the
perioperative outcome measures and oncological impact between minimally invasive and …

[HTML][HTML] Transabdominal Preperitoneal (TAPP) versus Lichtenstein operation for primary inguinal hernia repair–A systematic review and meta-analysis of randomized …

U Scheuermann, S Niebisch, O Lyros… - BMC surgery, 2017 - Springer
Abstract Background Transabdominal Preperitoneal (TAPP) and Lichtenstein operation are
established methods for inguinal hernia repair in clinical practice. Meta-analyses of …

[HTML][HTML] High miR-196a levels promote the oncogenic phenotype of colorectal cancer cells

CC Schimanski, K Frerichs, F Rahman… - World journal of …, 2009 - ncbi.nlm.nih.gov
METHODS: The impact of miR-196a on the restriction targets HoxA7, HoxB8, HoxC8 and
HoxD8 was analyzed by reverse transcription polymerase chain reaction (RT-PCR) after …

[HTML][HTML] Resection of the mesopancreas (RMP): a new surgical classification of a known anatomical space

I Gockel, M Domeyer, T Wolloscheck… - World journal of surgical …, 2007 - Springer
Background Prognosis after surgical therapy for pancreatic cancer is poor and has been
attributed to early lymph node involvement as well as to a strong tendency of cancer cells to …

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

TL Lenz, AJ Deutsch, B Han, X Hu, Y Okada, S Eyre… - Nature …, 2015 - nature.com
Human leukocyte antigen (HLA) genes confer substantial risk for autoimmune diseases on a
log-additive scale. Here we speculated that differences in autoantigen-binding repertoires …

[HTML][HTML] Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis

P Gharahkhani, RC Fitzgerald, TL Vaughan… - The lancet …, 2016 - thelancet.com
Background Oesophageal adenocarcinoma represents one of the fastest rising cancers in
high-income countries. Barrett's oesophagus is the premalignant precursor of oesophageal …

[HTML][HTML] Endoscopic and surgical resection of T1a/T1b esophageal neoplasms: a systematic review

G Sgourakis, I Gockel, H Lang - World Journal of Gastroenterology …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate potential therapeutic recommendations for endoscopic and surgical
resection of T1a/T1b esophageal neoplasms. METHODS: A thorough search of electronic …

Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into …

JS Ong, J An, X Han, MH Law, P Nandakumar… - Gut, 2022 - gut.bmj.com
Objective Gastro-oesophageal reflux disease (GERD) has heterogeneous aetiology
primarily attributable to its symptom-based definitions. GERD genome-wide association …

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia

I Gockel, J Becker, MM Wouters, S Niebisch… - Nature …, 2014 - nature.com
Idiopathic achalasia is characterized by a failure of the lower esophageal sphincter to relax
due to a loss of neurons in the myenteric plexus,. This ultimately leads to massive dilatation …