Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from
person to person and to persistently colonize the stomach. Their population structure is a …

Helicobacter pylori is the main cause of peptic ulceration, distal gastric adenocarcinoma,
and gastric lymphoma. Only 15% of those colonized develop disease, and pathogenesis …

Humans have been colonized by Helicobacter pylori for at least 50,000 years and probably
throughout their evolution. H. pylori has adapted to humans, colonizing children and …

Approximately 50% of Helicobacter pylori strains produce a cytotoxin, encoded by vacA, that
induces vacuolation of eukaryotic cells. Analysis of a clinically isolated tox-strain (Tx30a) …

BACKGROUND & AIMS:: The Helicobacter pylori gene cagA and s1 or m1 forms of vacA are
more common in disease-associated strains. Recently, forms of cagA encoding multiple type …

Heightened inflammatory response and cytokine expression in vivo to cagA+ Helicobacter
pylori strains. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …

Background & Aims: Helicobacter pylori is the main cause of peptic ulceration and gastric
adenocarcinoma. The vacuolating cytotoxin gene, vacA, is a major determinant of virulence …

BACKGROUND & AIMS: vacA encodes the vacuolating cytotoxin of Helicobacter pylori and
exhibits marked variation in signal sequence and midgene coding regions. The implications …

Abstract Background: Infection with Helicobacter pylori induces chronic gastritis in virtually
all infected persons, and such gastritis has been associated with an increased risk of …

The diversity of the gene encoding the vacuolating cytotoxin (vacA) of Helicobacter pylori
was analyzed in 98 isolates obtained from different geographic locations. The studies …