Eosinophilic esophagitis (EoE) is a clinicopathologic condition of increasing recognition and
prevalence. In 2007, a consensus recommendation provided clinical and histopathologic …

Abstract Chicago Classification v4. 0 (CCv4. 0) is the updated classification scheme for
esophageal motility disorders using metrics from high‐resolution manometry (HRM). Fifty …

Background & Aims Over the last decade, clinical experiences and research studies raised
concerns regarding use of proton pump inhibitors (PPIs) as part of the diagnostic strategy for …

Our objective was to obtain national data of the estimated prevalence, sociodemographic
relationships, and health impact of persons with functional gastrointestinal disorders. We …

BACKGROUND Endoscopic oesophageal changes are diagnostically helpful and identify
patients exposed to the risk of disease chronicity. However, there is a serious lack of …

OBJECTIVES: Limitations of catheter-based esophageal pH monitoring are discomfort,
inconvenience, and interference with normal activity. An alternative to conventional pH …

Although esophageal manometry is widely used in clinical practice, the normal range of
esophageal contraction parameters is poorly defined. Therefore, 95 healthy volunteers …

OBJECTIVE: In patients with gastroesophageal reflux disease (GERD), esomeprazole, the S-
isomer of omeprazole, has demonstrated pharmacological and clinical benefits beyond …

Achalasia is a rare motility disorder of the oesophagus characterised by loss of enteric
neurons leading to absence of peristalsis and impaired relaxation of the lower oesophageal …

BACKGROUND & AIMS: Acid and pepsin are known to cause esophagitis. However, the
role of duodenogastroesophageal reflux (DGER) in producing esophageal mucosal injury …