Background: Pyoderma gangrenosum (PG) is a chronic ulcerating skin condition that often
occurs in association with inflammatory bowel disease. There have been a number of …

Substance P (SP) can cause plasma leakage at sites of inflammation by binding to
neurokinin type 1 (NK1) receptors on the surface of endothelial cells. Internalization after …

Cytoplasmic vesicles, resembling synaptic vesicles of efferent nerve fibers,* are a distinctive
feature of sensory nerve fibers that innervate glomus cells of the carotid body (Biscoe et al …

Fifty consecutive patients with chronic airflow obstruction who were admitted to a respiratory
unit were assessed medically and psychiatrically. A high rate of psychiatric morbidity (58%) …

Taxonomic sufficiency, or the suitability of substituting higher level taxonomic designations
as response variables in community ecology analyses, is important in biodiversity studies …

Background Very few over‐the‐counter cosmetic 'anti‐ageing'products have been subjected
to a rigorous double‐blind, vehicle‐controlled trial of efficacy. Previously we have shown …

The response of body size to increasing temperature constitutes a universal response to
climate change that could strongly affect terrestrial ectotherms, but the magnitude and …

Recent changes in arctic vegetation might not be driven by climate change alone. Legacies
of human activities have received little attention as a contributing factor. We examine the …

The mechanisms by which respiratory syncytial virus (RSV) infection induces bronchiolitis
and airway disease are unclear. The presence of large numbers of polymorphonuclear …

Background Photoaged skin is characterized by coarse and fine wrinkles. The mechanism of
wrinkle formation appears to involve changes to components of the dermal extracellular …