User profiles for "author:J Krell"
 | Jonathan KrellSenior lecturer Imperial College Verified email at imperial.ac.uk Cited by 5089 |
The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper
…, MR Cappelletti, E Diaz-Rubio, J Krell… - Critical reviews in …, 2019 - Elsevier
Background The heterogeneity of metastatic breast cancer (MBC) necessitates novel
biomarkers allowing stratification of patients for treatment selection and drug development …
biomarkers allowing stratification of patients for treatment selection and drug development …
[HTML][HTML] microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis
Background Reports have described the prognostic relevance of microRNAs (miRNAs) in
patients treated for pancreatic ductal adenocarcinoma (PDAC). However, many of these …
patients treated for pancreatic ductal adenocarcinoma (PDAC). However, many of these …
Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data
…, F Consoli, A Bottini, E Diaz-Rubio, J Krell… - The lancet …, 2014 - thelancet.com
Background We aimed to assess the clinical validity of circulating tumour cell (CTC)
quantification for prognostication of patients with metastatic breast cancer by undertaking a …
quantification for prognostication of patients with metastatic breast cancer by undertaking a …
Emerging roles of competing endogenous RNAs in cancer: insights from the regulation of PTEN
A de Giorgio, J Krell, V Harding… - … and cellular biology, 2013 - Am Soc Microbiol
The capacity of noncoding RNA to regulate gene expression in health and disease is
epitomized by the microRNAs, small∼ 22-nucleotide RNAs that target mRNAs to repress …
epitomized by the microRNAs, small∼ 22-nucleotide RNAs that target mRNAs to repress …
The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella
T Heuser, M Raytchev, J Krell, ME Porter… - Journal of Cell …, 2009 - rupress.org
Cilia and flagella are highly conserved microtubule (MT)-based organelles with motile and
sensory functions, and ciliary defects have been linked to several human diseases. The 9+ 2 …
sensory functions, and ciliary defects have been linked to several human diseases. The 9+ 2 …
MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression
Background & Aims There has not been a broad analysis of the combined effects of altered
activities of microRNAs (miRNAs) in pancreatic ductal adenocarcinoma (PDAC) cells, and it …
activities of microRNAs (miRNAs) in pancreatic ductal adenocarcinoma (PDAC) cells, and it …
Patient‐derived xenografts for individualized care in advanced sarcoma
…, G Blackman, V Harding, D Vasquez, J Krell… - Cancer, 2014 - Wiley Online Library
BACKGROUND Patients with advanced, metastatic sarcoma have a poor prognosis, and the
overall benefit from the few standard‐of‐care therapeutics available is small. The rarity of …
overall benefit from the few standard‐of‐care therapeutics available is small. The rarity of …
[HTML][HTML] MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors
LR Jiao, AE Frampton, J Jacob, L Pellegrino, J Krell… - PloS one, 2012 - journals.plos.org
Background MicroRNA (miRNA) expression profiles have been described in pancreatic
ductal adenocarcinoma (PDAC), but these have not been compared with pre-malignant …
ductal adenocarcinoma (PDAC), but these have not been compared with pre-malignant …
General investigations on processing tool steel X40CrMoV5-1 with selective laser melting
J Krell, A Röttger, K Geenen, W Theisen - Journal of Materials Processing …, 2018 - Elsevier
Abstract The X40CrMoV5-1 (H13) hot work tool steel was densified by selective laser
melting (SLM) using different laser parameters and preheating temperatures. The porosity …
melting (SLM) using different laser parameters and preheating temperatures. The porosity …
A head‐to‐head comparison of ixekizumab vs. guselkumab in patients with moderate‐to‐severe plaque psoriasis: 12‐week efficacy, safety and speed of response …
A Blauvelt, K Papp, A Gottlieb, A Jarell… - British journal of …, 2020 - academic.oup.com
Background Patients with psoriasis value rapid and complete skin clearance. No head‐to‐
head studies have focused on early responses to interleukin (IL)‐17 vs. IL‐23 inhibitors …
head studies have focused on early responses to interleukin (IL)‐17 vs. IL‐23 inhibitors …