OBJECTIVES: The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)
program was initiated by the International Organization for the Study of Inflammatory Bowel …

Crohn's disease is a lifelong disease arising from an interaction between genetic and
environmental factors, but observed predominantly in developed countries of the world. The …

Aliment Pharmacol Ther 2011; 34: 125–145 Summary Background Cross‐sectional imaging
techniques, including ultrasonography (US), computed tomography (CT) and magnetic …

We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …

Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …

Background Tofacitinib, an oral, small-molecule Janus kinase inhibitor, was shown to have
potential efficacy as induction therapy for ulcerative colitis in a phase 2 trial. We further …

Background Upadacitinib, an oral selective Janus kinase (JAK) inhibitor, is under
investigation for the treatment of Crohn's disease. Methods In two phase 3 induction trials (U …

Background Complex perianal fistulas in Crohn's disease are challenging to treat.
Allogeneic, expanded, adipose-derived stem cells (Cx601) are a promising new therapeutic …

It has recently been shown that repeated large-volume paracentesis associated with
intravenous albumin infusion is a rapid, effective, and safe therapy of ascites in cirrhosis. To …

Crohn's disease (CD) is a chronic progressive destructive disease. Currently available
instruments measure disease activity at a specific point in time. An instrument to measure …