User profiles for "author:J-M Herbert"
John M. HerbertProfessor of Chemistry & Biochemistry, Ohio State University Verified email at chemistry.ohio-state.edu Cited by 15469 |
Advances in methods and algorithms in a modern quantum chemistry program package
Advances in theory and algorithms for electronic structure calculations must be incorporated
into program packages to enable them to become routinely used by the broader chemical …
into program packages to enable them to become routinely used by the broader chemical …
Identification and biological activity of the active metabolite of clopidogrel
P Savi, JM Pereillo, MF Uzabiaga… - Thrombosis and …, 2000 - thieme-connect.com
Like ticlopidine, the ADP receptor antagonist clopidogrel is inactive in vitro and must be
administered iv or orally to exhibit antiaggregatory and antithrombotic activities. We have …
administered iv or orally to exhibit antiaggregatory and antithrombotic activities. We have …
Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis
P Savi, JM Herbert - Seminars in thrombosis and hemostasis, 2005 - thieme-connect.com
Ticlopidine and clopidogrel belong to the same chemical family of thienopyridine adenosine
diphosphate (ADP)-receptor antagonists. They have shown their efficacy as platelet …
diphosphate (ADP)-receptor antagonists. They have shown their efficacy as platelet …
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
P Carmeliet, L Moons, A Luttun, V Vincenti… - Nature medicine, 2001 - nature.com
Vascular endothelial growth factor (VEGF) stimulates angiogenesis by activating VEGF
receptor-2 (VEGFR-2). The role of its homolog, placental growth factor (PlGF), remains …
receptor-2 (VEGFR-2). The role of its homolog, placental growth factor (PlGF), remains …
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
P Carmeliet, Y Dor, JM Herbert, D Fukumura… - Nature, 1998 - nature.com
As a result of deprivation of oxygen (hypoxia) and nutrients, the growth and viability of cells
is reduced. Hypoxia-inducible factor (HIF)-1α helps to restore oxygen homeostasis by …
is reduced. Hypoxia-inducible factor (HIF)-1α helps to restore oxygen homeostasis by …
[BOOK][B] Electroceramics: materials, properties, applications
AJ Moulson, JM Herbert - 2003 - books.google.com
Electroceramics, Materials, Properties, Applications, Second Edition provides a
comprehensive treatment of the many aspects of ceramics and their electrical applications …
comprehensive treatment of the many aspects of ceramics and their electrical applications …
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
B Oosthuyse, L Moons, E Storkebaum, H Beck… - Nature …, 2001 - nature.com
Hypoxia stimulates angiogenesis through the binding of hypoxia-inducible factors to the
hypoxia-response element in the vascular endothelial growth factor (Vegf) promotor. Here …
hypoxia-response element in the vascular endothelial growth factor (Vegf) promotor. Here …
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
A Luttun, M Tjwa, L Moons, Y Wu… - Nature medicine, 2002 - nature.com
The therapeutic potential of placental growth factor (PlGF) and its receptor Flt1 in
angiogenesis is poorly understood. Here, we report that PlGF stimulated angiogenesis and …
angiogenesis is poorly understood. Here, we report that PlGF stimulated angiogenesis and …
[HTML][HTML] Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
P Carmeliet, MG Lampugnani, L Moons, F Breviario… - Cell, 1999 - cell.com
Vascular endothelial cadherin, VE-cadherin, mediates adhesion between endothelial cells
and may affect vascular morphogenesis via intracellular signaling, but the nature of these …
and may affect vascular morphogenesis via intracellular signaling, but the nature of these …
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure
Cardiac rupture is a fatal complication of acute myocardial infarction lacking treatment. Here,
acute myocardial infarction resulted in rupture in wild-type mice and in mice lacking tissue …
acute myocardial infarction resulted in rupture in wild-type mice and in mice lacking tissue …