Background There is increasing concern about the apparently rising incidence and
worsening outcome of Clostridium difficile infection (CDI) associated with inflammatory …

Background Anti-TNF drugs are effective treatments for the management of Crohn's disease
but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors …

Objective Delayed second dose SARS-CoV-2 vaccination trades maximal effectiveness for a
lower level of immunity across more of the population. We investigated whether patients with …

Background The effects that therapies for inflammatory bowel disease (IBD) have on
immune responses to SARS-CoV-2 vaccination are not yet fully known. Therefore, we …

The World Health Organization has recommended the integrated model of care as the
current best practice of care, and, in recent years, it has been gaining popularity worldwide …

Background & Aims Anti–tumor necrosis factor (anti-TNF) therapies are the most widely
used biologic drugs for treating immune-mediated diseases, but repeated administration can …

There is increasing evidence that psychological stress and associated mood disorders are
linked with, and can adversely affect the course of, inflammatory bowel disease (IBD) …

Anti tumour necrosis factor (anti-TNF) drugs increase the risk of serious respiratory infection
and impair protective immunity following pneumococcal and influenza vaccination. Here we …

Objective Antitumour necrosis factor (anti-TNF) drugs impair protective immunity following
pneumococcal, influenza and viral hepatitis vaccination and increase the risk of serious …

Background Children and adolescents with inflammatory bowel disease (IBD) are more
likely to have Crohn's disease (CD) than ulcerative colitis (UC) and their disease tends to be …