User profiles for "author:Jared A Weis"
Jared A. WeisAssistant Professor, Wake Forest School of Medicine Verified email at wakehealth.edu Cited by 3148 |
Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair
F Granero-Molto, JA Weis, L Longobardi… - Expert opinion on …, 2008 - Taylor & Francis
Background: Mesenchymal stem cells (MSC) are multipotent cells with the ability to
differentiate into mesenchyme-derived cells including osteoblasts and chondrocytes …
differentiate into mesenchyme-derived cells including osteoblasts and chondrocytes …
Clinically relevant modeling of tumor growth and treatment response
Current mathematical models of tumor growth are limited in their clinical application
because they require input data that are nearly impossible to obtain with sufficient spatial …
because they require input data that are nearly impossible to obtain with sufficient spatial …
Regenerative effects of transplanted mesenchymal stem cells in fracture healing
Mesenchymal stem cells (MSC) have a therapeutic potential in patients with fractures to
reduce the time of healing and treat nonunions. The use of MSC to treat fractures is attractive …
reduce the time of healing and treat nonunions. The use of MSC to treat fractures is attractive …
Multi-scale modeling in clinical oncology: opportunities and barriers to success
Hierarchical processes spanning several orders of magnitude of both space and time
underlie nearly all cancers. Multi-scale statistical, mathematical, and computational …
underlie nearly all cancers. Multi-scale statistical, mathematical, and computational …
TGF-β signaling is essential for joint morphogenesis
A Spagnoli, L O'Rear, RL Chandler… - The Journal of cell …, 2007 - rupress.org
Despite its clinical significance, joint morphogenesis is still an obscure process. In this study,
we determine the role of transforming growth factor β (TGF-β) signaling in mice lacking the …
we determine the role of transforming growth factor β (TGF-β) signaling in mice lacking the …
Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression
Objectives Spasmolytic polypeptide-expressing metaplasia (SPEM) develops as a
preneoplastic lesion in the stomachs of mice and humans after parietal cell loss. To identify …
preneoplastic lesion in the stomachs of mice and humans after parietal cell loss. To identify …
Predicting the response of breast cancer to neoadjuvant therapy using a mechanically coupled reaction–diffusion model
Although there are considerable data on the use of mathematical modeling to describe
tumor growth and response to therapy, previous approaches are often not of the form that …
tumor growth and response to therapy, previous approaches are often not of the form that …
Mesenchymal Stem Cells Expressing Insulin-like Growth Factor-I (MSCIGF) Promote Fracture Healing and Restore New Bone Formation in Irs1 Knockout Mice: Analyses of MSC …
F Granero-Moltó, TJ Myers, JA Weis, L Longobardi… - Stem Cells, 2011 - academic.oup.com
Failures of fracture repair (nonunions) occur in 10% of all fractures. The use of mesenchymal
stem cells (MSC) in tissue regeneration appears to be rationale, safe, and feasible. The …
stem cells (MSC) in tissue regeneration appears to be rationale, safe, and feasible. The …
Near real-time computer assisted surgery for brain shift correction using biomechanical models
Conventional image-guided neurosurgery relies on preoperative images to provide surgical
navigational information and visualization. However, these images are no longer accurate …
navigational information and visualization. However, these images are no longer accurate …
A mechanically coupled reaction–diffusion model that incorporates intra-tumoural heterogeneity to predict in vivo glioma growth
DA Hormuth, JA Weis, SL Barnes… - Journal of The …, 2017 - royalsocietypublishing.org
While gliomas have been extensively modelled with a reaction–diffusion (RD) type equation
it is most likely an oversimplification. In this study, three mathematical models of glioma …
it is most likely an oversimplification. In this study, three mathematical models of glioma …