Ustekinumab for the treatment of refractory Crohn's disease: the Spanish experience in a large multicentre open-label cohort
S Khorrami, D Ginard, I Marín-Jiménez… - Inflammatory bowel …, 2016 - academic.oup.com
Background Ustekinumab is a fully human monoclonal antibody against IL-12/23.
Ustekinumab induced clinical response and maintained higher rate of response than …
Ustekinumab induced clinical response and maintained higher rate of response than …
[PDF][PDF] Impact of anticoagulation on upper‐gastrointestinal bleeding in cirrhosis. A retrospective multicenter study
F Cerini, JM Gonzalez, F Torres, Á Puente… - …, 2015 - Wiley Online Library
Recent studies have shown that liver cirrhosis (LC) behaves as an acquired
hypercoagulable state with increased thrombotic risk. This is why anticoagulation therapy …
hypercoagulable state with increased thrombotic risk. This is why anticoagulation therapy …
The earliest maize from San Marcos Tehuacán is a partial domesticate with genomic evidence of inbreeding
M Vallebueno-Estrada… - Proceedings of the …, 2016 - National Acad Sciences
Pioneering archaeological expeditions lead by Richard MacNeish in the 1960s identified the
valley of Tehuacán as an important center of early Mesoamerican agriculture, providing by …
valley of Tehuacán as an important center of early Mesoamerican agriculture, providing by …
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study
JJ Swen, CH van der Wouden, LEN Manson… - The Lancet, 2023 - thelancet.com
Background The benefit of pharmacogenetic testing before starting drug therapy has been
well documented for several single gene–drug combinations. However, the clinical utility of …
well documented for several single gene–drug combinations. However, the clinical utility of …
Hepatic encephalopathy is not a contraindication to pre-emptive TIPS in high-risk patients with cirrhosis with variceal bleeding
M Rudler, V Hernández-Gea, BD Procopet, A Giráldez… - Gut, 2023 - gut.bmj.com
Background A pre-emptive transjugular intrahepatic portosystemic shunt (pTIPS) reduces
mortality in high-risk patients with cirrhosis (Child-Pugh C/B+ active bleeding) with acute …
mortality in high-risk patients with cirrhosis (Child-Pugh C/B+ active bleeding) with acute …
[HTML][HTML] Sulforaphane modulates the inflammation and delays neurodegeneration on a retinitis pigmentosa mice model
A Canto, J Martínez-González, M Miranda… - Frontiers in …, 2022 - frontiersin.org
The term retinitis pigmentosa (RP) describes a large group of hereditary retinopathies. From
a cellular view, retinal degeneration is prompted by an initial death of rods, followed later by …
a cellular view, retinal degeneration is prompted by an initial death of rods, followed later by …
Cost effectiveness of bemiparin sodium versus unfractionated heparin and oral anticoagulants in the acute and long-term treatment of deep vein thrombosis
A Gomez-Outes, E Rocha, J Martínez-González… - …, 2006 - Springer
Introduction: Low-molecular-weight heparins (LMWHs) are at least as effective and well
tolerated as unfractionated heparin (UFH) in the treatment of deep vein thrombosis (DVT) …
tolerated as unfractionated heparin (UFH) in the treatment of deep vein thrombosis (DVT) …
[HTML][HTML] Time-course changes in oxidative stress and inflammation in the retinas of rds mice: A retinitis pigmentosa model
A Cantó, J Martínez-González, I Almansa… - Antioxidants, 2022 - mdpi.com
(1) Background: Retinitis pigmentosa (RP) is characterized by progressive photoreceptor
death. A Prph2Rd2 or an rds mouse is an RP model that closely reflects human RP. The …
death. A Prph2Rd2 or an rds mouse is an RP model that closely reflects human RP. The …
Thromboprophylaxis with the low-molecular-weight heparin bemiparin sodium in elderly medical patients in usual clinical practice: the ANCIANOS study
L Rodriguez-Manas, R Gomez-Huelgas… - Clinical drug …, 2010 - Springer
Background: Venous thromboembolism (VTE) is a preventable common disease in geriatric
medical patients, causing substantial morbidity and mortality. Objective: To assess the …
medical patients, causing substantial morbidity and mortality. Objective: To assess the …
[HTML][HTML] Genetic variants affecting anti-VEGF drug response in polypoidal choroidal vasculopathy patients: a systematic review and meta-analysis
X Díaz-Villamarín, D Blánquez-Martínez… - Genes, 2020 - mdpi.com
Polypoidal choroidal vasculopathy (PCV) is usually regarded as a subtype of choroidal
neovascularization (CNV) that is secondary to age-related macular degeneration (AMD) …
neovascularization (CNV) that is secondary to age-related macular degeneration (AMD) …