User profiles for "author:Jean-François Dufour"

Jean-François Dufour

Swiss Foundation againt Liver Cancer
Verified email at svmed.ch
Cited by 43161

A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement

M Eslam, PN Newsome, SK Sarin, QM Anstee… - Journal of …, 2020 - Elsevier
The exclusion of other chronic liver diseases including “excess” alcohol intake has until now
been necessary to establish a diagnosis of metabolic dysfunction-associated fatty liver …

Angiogenesis and hepatocellular carcinoma

D Semela, JF Dufour - Journal of hepatology, 2004 - Elsevier
With more than half a million new cases each year, hepatocellular carcinoma (HCC) is the
fifth most common tumor worldwide and the third cause of cancer-related deaths [1]. At the …

[HTML][HTML] Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: a systematic review and meta-analysis

EA Selvaraj, FE Mózes, ANA Jayaswal… - Journal of …, 2021 - Elsevier
Background and Aims Vibration-controlled transient elastography (VCTE), point shear wave
elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic …

Association between sustained virological response and all-cause mortality among patients with chronic hepatitis C and advanced hepatic fibrosis

AJ Van Der Meer, BJ Veldt, JJ Feld, H Wedemeyer… - Jama, 2012 - jamanetwork.com
Context Chronic hepatitis C virus (HCV) infection outcomes include liver failure,
hepatocellular carcinoma (HCC), and liver-related death. Objective To assess the …

Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

ZM Younossi, V Ratziu, R Loomba, M Rinella… - The Lancet, 2019 - thelancet.com
Background Non-alcoholic steatohepatitis (NASH) is a common type of chronic liver disease
that can lead to cirrhosis. Obeticholic acid, a farnesoid X receptor agonist, has been shown …

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

A Rauch, Z Kutalik, P Descombes, T Cai, J Di Iulio… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Hepatitis C virus (HCV) induces chronic infection in 50% to 80% of
infected persons; approximately 50% of these do not respond to therapy. We performed a …

Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitis

JF Dufour, CM Oneta, JJ Gonvers, F Bihl… - Clinical …, 2006 - Elsevier
Background & Aims: Nonalcoholic steatohepatitis (NASH) is a frequent liver disease that can
progress to cirrhosis and for which there is no recognized therapy. UDCA and vitamin E …

Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised …

M Manns, D Samuel, EJ Gane, D Mutimer… - The Lancet Infectious …, 2016 - thelancet.com
Background Treatment options are limited for patients infected by hepatitis C virus (HCV)
with advanced liver disease. We assessed the safety and efficacy of ledipasvir, sofosbuvir …

Global multi-stakeholder endorsement of the MAFLD definition

N Méndez-Sánchez, E Bugianesi, RG Gish… - The lancet …, 2022 - thelancet.com
Correspondence 390 www. thelancet. com/gastrohep Vol 7 May 2022 at least two different
mechanisms of action. Views were divided on the failure of immunomodulators, with 252 …

[HTML][HTML] Prognosis of patients with hepatocellular carcinoma treated with immunotherapy–development and validation of the CRAFITY score

B Scheiner, K Pomej, MM Kirstein, F Hucke… - Journal of …, 2022 - Elsevier
Background & Aims Immunotherapy with atezolizumab plus bevacizumab represents the
new standard of care in systemic front-line treatment of hepatocellular carcinoma (HCC) …