[HTML][HTML] Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …
and influence cellular function via effects on membrane properties, and also by acting as a …
Are Alkyne Reductions Chemo-, Regio-, and Stereoselective Enough To Provide Pure (Z)-Olefins in Polyfunctionalized Bioactive Molecules?
C Oger, L Balas, T Durand, JM Galano - Chemical reviews, 2013 - ACS Publications
Many biologically active molecules incorporate carbon− carbon double bond (s) with well-
defined configurations (E or Z), such as β-carotene, 1 polyene antifungal drugs, 2, 3 …
defined configurations (E or Z), such as β-carotene, 1 polyene antifungal drugs, 2, 3 …
[PDF][PDF] Physiological role of reactive oxygen species as promoters of natural defenses
J Roy, JM Galano, T Durand, JY Le Guennec… - FASEB …, 2017 - hal.umontpellier.fr
It has been 60 yr since the discovery of reactive oxygen species (ROS) in biology and the
beginning of the scientific community's attempt to understand the impact of the unpaired …
beginning of the scientific community's attempt to understand the impact of the unpaired …
Beyond prostaglandins—chemistry and biology of cyclic oxygenated metabolites formed by free‐radical pathways from polyunsaturated fatty acids
U Jahn, JM Galano, T Durand - … Chemie International Edition, 2008 - Wiley Online Library
Polyunsaturated fatty acids (PUFAs) are important constituents in all organisms. They fulfil
many functions, ranging from modulating the structure of membranes to acting as precursors …
many functions, ranging from modulating the structure of membranes to acting as precursors …
[HTML][HTML] Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages
Oxidized low-density lipoprotein (oxLDL) is a well-recognized proatherogenic particle that
functions in atherosclerosis. In this study, we established conditions to generate human …
functions in atherosclerosis. In this study, we established conditions to generate human …
Isoprostanes, neuroprostanes and phytoprostanes: An overview of 25 years of research in chemistry and biology
JM Galano, YY Lee, C Oger, C Vigor… - Progress in lipid …, 2017 - Elsevier
Since the beginning of the 1990's diverse types of metabolites originating from
polyunsaturated fatty acids, formed under autooxidative conditions were discovered. Known …
polyunsaturated fatty acids, formed under autooxidative conditions were discovered. Known …
[HTML][HTML] Oxidative brain damage in Mecp2-mutant murine models of Rett syndrome
C De Felice, F Della Ragione, C Signorini… - Neurobiology of …, 2014 - Elsevier
Rett syndrome (RTT) is a rare neurodevelopmental disorder affecting almost exclusively
females, caused in the overwhelming majority of the cases by loss-of-function mutations in …
females, caused in the overwhelming majority of the cases by loss-of-function mutations in …
[HTML][HTML] Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917
T Pérez-Berezo, J Pujo, P Martin, P Le Faouder… - Nature …, 2017 - nature.com
Administration of the probiotic Escherichia coli strain Nissle 1917 (EcN) decreases visceral
pain associated with irritable bowel syndrome. Mutation of clbA, a gene involved in the …
pain associated with irritable bowel syndrome. Mutation of clbA, a gene involved in the …
Non-enzymatic lipid oxidation products in biological systems: assessment of the metabolites from polyunsaturated fatty acids
C Vigor, J Bertrand-Michel, E Pinot, C Oger… - … of Chromatography B, 2014 - Elsevier
Metabolites of non-enzymatic lipid peroxidation of polyunsaturated fatty acids notably
omega-3 and omega-6 fatty acids have become important biomarkers of lipid products …
omega-3 and omega-6 fatty acids have become important biomarkers of lipid products …
Isoprostanes and neuroprostanes: total synthesis, biological activity and biomarkers of oxidative stress in humans
JM Galano, E Mas, A Barden, TA Mori… - Prostaglandins & other …, 2013 - Elsevier
Abstract Isoprostanes (IsoPs) and neuroprostanes (NeuroPs) are formed in vivo by a free
radical non-enzymatic mechanism involving peroxidation of arachidonic acid (AA, C20: 4 n …
radical non-enzymatic mechanism involving peroxidation of arachidonic acid (AA, C20: 4 n …