HPV testing on self collected cervicovaginal lavage specimens as screening method for women who do not attend cervical screening: cohort study

M Gök, DAM Heideman, FJ van Kemenade, J Berkhof… - Bmj, 2010 - bmj.com
Objective To determine whether offering self sampling of cervicovaginal material for high risk
human papillomavirus (HPV) testing is an effective screening method for women who do not …

A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp

MA Nolte, JAM Beliën, I Schadee-Eestermans… - The Journal of …, 2003 - rupress.org
Access to the splenic white pulp is restricted to lymphocytes and dendritic cells. Here we
show that movement of molecules from the blood into these confined areas is also limited …

[HTML][HTML] Rapid quantification of myocardial fibrosis: a new macro-based automated analysis

AM Hadi, KTB Mouchaers, I Schalij, K Grunberg… - Cellular oncology, 2011 - Springer
Background Fibrosis is associated with various cardiac pathologies and dysfunction. Current
quantification methods are time-consuming and laborious. We describe a semi-automated …

Astrocytic Aβ1‐42 uptake is determined by Aβ‐aggregation state and the presence of amyloid‐associated proteins

HM Nielsen, SD Mulder, JAM Beliën, RJP Musters… - Glia, 2010 - Wiley Online Library
Intracerebral accumulation of amyloid‐β (Aβ) leading to Aβ plaque formation, is the main
hallmark of Alzheimer's disease and might be caused by defective Aβ‐clearance. We …

Drug resistance-associated marker Lrp for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma

MA Lzquierdo, AGJ Zee, JB Vermorken… - JNCI: Journal of the …, 1995 - academic.oup.com
Background: Drug resistance is a major impediment to the successful treatment of ovarian
carcinoma. None of the earlier-identified resistance mechanisms, such as overexpression of …

Experience with high‐risk human papillomavirus testing on vaginal brush‐based self‐samples of non‐attendees of the cervical screening program

M Gök, FJ van Kemenade… - … journal of cancer, 2012 - Wiley Online Library
We evaluated the effect of offering brush‐based vaginal self‐sampling for high‐risk human
papillomavirus (hrHPV) testing to non‐attendees of the cervical screening program on …

TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression

AH Sillars-Hardebol, B Carvalho, M Tijssen… - Gut, 2012 - gut.bmj.com
Background and objective Progression of a colorectal adenoma to invasive cancer occurs in
a minority of adenomas and is the most crucial step in colorectal cancer pathogenesis. In the …

[HTML][HTML] Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis

JACM Goos, VMH Coupe, B Diosdado… - British journal of …, 2013 - nature.com
Background: Five-year survival after resection of colorectal cancer liver metastasis (CRLCM)
is< 30%. We recently found that aurora kinase A (AURKA) drives 20q gain-associated …

Changes in tissue composition of the vaginal wall of premenopausal women with prolapse

MH Kerkhof, AM Ruiz-Zapata, H Bril… - American journal of …, 2014 - Elsevier
Objective The objective of this study was to compare histological and biochemical features
of the (normal) precervical anterior vaginal wall and the prolapsed anterior vaginal wall of …

Prognostic value of DNA ploidy status in patients with oral leukoplakia

JF Bremmer, RH Brakenhoff, MAM Broeckaert… - Oral oncology, 2011 - Elsevier
Oral leukoplakia is a potentially malignant disorder that will develop into oral cancer at an
estimated rate of 1–2% per year. Aim of the present study is to assess the possible predictive …