Therapeutic strategies for hepatitis B virus infection: towards a cure

GC Fanning, F Zoulim, J Hou, A Bertoletti - Nature reviews Drug …, 2019 - nature.com
Chronic hepatitis B virus (HBV) infection is a common cause of liver disease globally, with a
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …

Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission

GS Cooke, I Andrieux-Meyer, TL Applegate… - The lancet …, 2019 - thelancet.com
Viral hepatitis is a major public health threat and a leading cause of death worldwide.
Annual mortality from viral hepatitis is similar to that of other major infectious diseases such …

[HTML][HTML] Management of patients with liver derangement during the COVID-19 pandemic: an Asia-Pacific position statement

GLH Wong, VWS Wong, A Thompson, J Jia… - The Lancet …, 2020 - thelancet.com
The COVID-19 pandemic has spread rapidly worldwide. It is common to encounter patients
with COVID-19 with abnormal liver function, either in the form of hepatitis, cholestasis, or …

Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS‐CoV) in SARS patients: implications for pathogenesis and virus …

Y Ding, LI He, Q Zhang, Z Huang, X Che… - The Journal of …, 2004 - Wiley Online Library
We previously identified the major pathological changes in the respiratory and immune
systems of patients who died of severe acute respiratory syndrome (SARS) but gained little …

[HTML][HTML] Seroprevalence of immunoglobulin M and G antibodies against SARS-CoV-2 in China

X Xu, J Sun, S Nie, H Li, Y Kong, M Liang, J Hou… - Nature medicine, 2020 - nature.com
Detection of asymptomatic or subclinical novel human coronavirus SARS-CoV-2 infection is
critical for understanding the overall prevalence and infection potential of COVID-19. To …

[HTML][HTML] Epidemiology and prevention of hepatitis B virus infection

J Hou, Z Liu, F Gu - International journal of medical sciences, 2005 - ncbi.nlm.nih.gov
Hepatitis B is one of the most common infectious diseases globally. It has been estimated
that there are 350 million chronic hepatitis B virus (HBV) carriers worldwide. The prevalence …

[HTML][HTML] Serum hepatitis B virus RNA is encapsidated pregenome RNA that may be associated with persistence of viral infection and rebound

J Wang, T Shen, X Huang, GR Kumar, X Chen… - Journal of …, 2016 - Elsevier
Background & Aims Hepatitis B virus (HBV) RNA in serum has recently been linked to
efficacy and prognosis of chronic hepatitis B (CHB) treatment. This study explored the …

[HTML][HTML] Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double‐blind trial

J Hou, YK Yin, D Xu, D Tan, J Niu, X Zhou… - …, 2008 - Wiley Online Library
Chronic hepatitis B and its life‐threatening sequelae are highly prevalent in China. There is
a need for effective new therapies to suppress hepatitis B virus (HBV) replication and …

[HTML][HTML] aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis

R Fan, G Papatheodoridis, J Sun, H Innes… - Journal of …, 2020 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) is the leading cause of death in
patients with chronic hepatitis. In this international collaboration, we sought to develop a …

Switching from entecavir to PegIFN alfa-2a in patients with HBeAg-positive chronic hepatitis B: a randomised open-label trial (OSST trial)

Q Ning, M Han, Y Sun, J Jiang, D Tan, J Hou… - Journal of …, 2014 - Elsevier
Background & Aims Durable post-treatment response is uncommon in chronic hepatitis B
(CHB) patients on nucleos (t) ide analogue therapy. Response, response predictors and …