User profiles for "author:Jochen Maul"

Dr. med. Jochen Maul, FEBGH

Gastroenterologist, Gastroenterologie am Bayerischen Platz, Berlin; visiting scholar Charité
Verified email at charite.de
Cited by 3401

Peripheral and intestinal regulatory CD4+ CD25high T cells in inflammatory bowel disease

J Maul, C Loddenkemper, P Mundt, E Berg, T Giese… - Gastroenterology, 2005 - Elsevier
Background & Aims: Regulatory CD25+ T cells (Treg) are effective in the prevention and
down-regulation of inflammatory bowel disease (IBD) in animal models. Functional Treg …

[PDF][PDF] Human anti-fungal Th17 immunity and pathology rely on cross-reactivity against Candida albicans

P Bacher, T Hohnstein, E Beerbaum, M Röcker… - Cell, 2019 - cell.com
Th17 cells provide protection at barrier tissues but may also contribute to immune pathology.
The relevance and induction mechanisms of pathologic Th17 responses in humans are …

Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART

HJ Epple, C Loddenkemper, D Kunkel, H Tröger… - Blood, 2006 - ashpublications.org
Recent evidence indicates that regulatory T cells (Tregs) play an important role in HIV
infection. However, although the gastrointestinal mucosa is a key compartment in HIV …

Use of intestinal ultrasound to monitor Crohn's disease activity

T Kucharzik, BM Wittig, U Helwig, N Börner… - Clinical …, 2017 - Elsevier
Background & Aims We performed a multicenter study to determine whether transabdominal
bowel wall ultrasonography, a noninvasive procedure that does not require radiation, can be …

Vedolizumab induction therapy for inflammatory bowel disease in clinical practice–a nationwide consecutive German cohort study

DC Baumgart, B Bokemeyer, A Drabik… - Alimentary …, 2016 - Wiley Online Library
Background Vedolizumab (VDZ) is a humanised monoclonal IgG1 antibody targeting α4β7
integrin. Aim To investigate the real‐world efficacy of vedolizumab for the treatment of …

Combination immunomodulator and antibiotic treatment in patients with inflammatory bowel disease and Clostridium difficile infection

S Ben-Horin, M Margalit, P Bossuyt, J Maul… - Clinical …, 2009 - Elsevier
BACKGROUND & AIMS: Management of Clostridium difficile infection in patients with flaring
inflammatory bowel disease (IBD) has not been optimized. We investigated the effects of …

[HTML][HTML] Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn's disease

GR Martini, E Tikhonova, E Rosati, MB DeCelie… - Nature medicine, 2023 - nature.com
Aberrant CD4+ T cell reactivity against intestinal microorganisms is considered to drive
mucosal inflammation in inflammatory bowel diseases. The disease-relevant microbial …

Prevalence and clinical impact of endoscopic pseudomembranes in patients with inflammatory bowel disease and Clostridium difficile infection

S Ben-Horin, M Margalit, P Bossuyt… - Journal of Crohn's …, 2010 - academic.oup.com
Background and aim: Limited data suggests that pseudomembranes are uncommon in
patients with inflammatory bowel disease (IBD) and C. difficile associated disease (CDAD) …

Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome

M Heindl, N Händel, J Ngeow, J Kionke, C Wittekind… - Gastroenterology, 2012 - Elsevier
The Phosphatase And Tensin Homolog Deleted On Chromosome 10 (PTEN) regulates the
phosphoinositol-3-kinase (PI3K)-AKT signaling pathway. In a series of 34 patients with …

H1N1 vaccines in a large observational cohort of patients with inflammatory bowel disease treated with immunomodulators and biological therapy

JF Rahier, P Papay, J Salleron, S Sebastian, M Marzo… - Gut, 2011 - gut.bmj.com
Background Safety data are lacking on influenza vaccination in general and on A (H1N1) v
vaccination in particular in patients with inflammatory bowel disease (IBD) receiving …