The human gut harbors more than 100 trillion microbial cells, which have an essential role in
human metabolic regulation via their symbiotic interactions with the host. Altered gut …

The human gut is a home for more than 100 trillion bacteria, far more than all other microbial
populations resident on the body's surface. The human gut microbiome is considered as a …

Obesity and type 2 diabetes are associated with low-grade inflammation and specific
changes in gut microbiota composition,,,,,,. We previously demonstrated that administration …

Objective Individuals with obesity and type 2 diabetes differ from lean and healthy
individuals in their abundance of certain gut microbial species and microbial gene richness …

Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …

The human gut microbiome is known to be associated with various human disorders, but a
major challenge is to go beyond association studies and elucidate causalities. Mathematical …

During the transition from a healthy state to cardiometabolic disease, patients become
heavily medicated, which leads to an increasingly aberrant gut microbiome and serum …

Previous microbiome and metabolome analyses exploring non-communicable diseases
have paid scant attention to major confounders of study outcomes, such as common, pre …

As solid tumors expand, oxygen and nutrients become limiting owing to inadequate
vascularization and diffusion. How malignant cells cope with this potentially lethal metabolic …

Background The dietary methylamines choline, carnitine, and phosphatidylcholine are used
by the gut microbiota to produce a range of metabolites, including trimethylamine (TMA) …