Abnormal intestinal permeability predicts relapse in inactive Crohn disease
IDR Arnott, K Kingstone, S Ghosh - Scandinavian journal of …, 2000 - Taylor & Francis
Background: Trials of maintenance therapy in quiescent Crohn disease are often
underpowered and there is need for objective markers that predict relapse. Intestinal …
underpowered and there is need for objective markers that predict relapse. Intestinal …
The diagnostic accuracy of fecal calprotectin during the investigation of suspected pediatric inflammatory bowel disease
…, SJ Lawrence, NA Kennedy, K Kingstone… - Official journal of the …, 2012 - journals.lww.com
OBJECTIVES: Fecal calprotectin (FC) is elevated in patients with inflammatory bowel
disease (IBD). Studies evaluating FC during the initial investigation of children with …
disease (IBD). Studies evaluating FC during the initial investigation of children with …
Clinical utility and diagnostic accuracy of faecal calprotectin for IBD at first presentation to gastroenterology services in adults aged 16–50 years
…, M Muscat, BW Gordon, K Kingstone… - Journal of Crohn's …, 2015 - academic.oup.com
Background: Distinguishing inflammatory bowel disease (IBD) from functional
gastrointestinal (GI) disease remains an important issue for gastroenterologists and primary …
gastrointestinal (GI) disease remains an important issue for gastroenterologists and primary …
Coeliac disease and malignancies
A Ferguson, K Kingstone - Acta Paediatrica, 1996 - Wiley Online Library
When compared with the general population, patients with coeliac disease (CD) have an
increased risk of developing enteropathy‐associated T‐cell lymphoma (EATCL) …
increased risk of developing enteropathy‐associated T‐cell lymphoma (EATCL) …
Intestinal antibody pattern of coeliac disease: association with gamma/delta T cell receptor expression by intraepithelial lymphocytes, and other indices of potential …
E Arranz, J Bode, K Kingstone, A Ferguson - Gut, 1994 - gut.bmj.com
Patients with coeliac disease have IgM antibodies and IgA anti-gliadin antibody in gut
secretions, and also high counts of intraepithelial lymphocytes (IEL) that express the …
secretions, and also high counts of intraepithelial lymphocytes (IEL) that express the …
Relevance of thiopurine methyltransferase activity in inflammatory bowel disease patients maintained on low‐dose azathioprine
S Campbell, K Kingstone… - Alimentary pharmacology & …, 2002 - Wiley Online Library
Background: It is well‐recognized that patients with low thiopurine methyltransferase activity
are more susceptible to the development of bone marrow suppression side‐effects. Aim: To …
are more susceptible to the development of bone marrow suppression side‐effects. Aim: To …
Heterogeneity of celiac disease: clinical, pathological, immunological, and genetic
…, H Gillett, K Humphreys, K Kingstone - Annals of the New …, 1998 - Wiley Online Library
In this paper we consider recent new data on the pathological features of gluten sensitivity
and on the disease‐associated antigens, in the context of a multistage hypothesis that we …
and on the disease‐associated antigens, in the context of a multistage hypothesis that we …
An evaluation of the use of serum 7-alpha-hydroxycholestenone as a diagnostic test of bile acid malabsorption causing watery diarrhea
WG Brydon, P Culbert, K Kingstone, A Jarvie… - Canadian Journal of …, 2011 - hindawi.com
BACKGROUND: Bile acid malabsorption (BAM) is a recognized cause of watery diarrhea,
often diagnosed empirically based on clinical response to cholestyramine. The radionuclide …
often diagnosed empirically based on clinical response to cholestyramine. The radionuclide …
Anti-endomysial antibody negative celiac disease
A Dahele, K Kingstone, J Bode, D Anderson… - Digestive diseases and …, 2001 - Springer
Anti-endomysium antibodies (AEM) fail to identify all untreated celiac disease (CD) patients.
This study aims to determine if additional serology, in particular, IgA anti-tissue …
This study aims to determine if additional serology, in particular, IgA anti-tissue …
Limitations of faecal elastase-1 and chymotrypsin as tests of exocrine pancreatic disease in adults
WG Brydon, K Kingstone… - Annals of clinical …, 2004 - journals.sagepub.com
Background: The faecal enzymes elastase and chymotrypsin are a relatively inexpensive
non-invasive means of investigating causes of malabsorption. However, such tests may be …
non-invasive means of investigating causes of malabsorption. However, such tests may be …