Background: Trials of maintenance therapy in quiescent Crohn disease are often
underpowered and there is need for objective markers that predict relapse. Intestinal …

OBJECTIVES: Fecal calprotectin (FC) is elevated in patients with inflammatory bowel
disease (IBD). Studies evaluating FC during the initial investigation of children with …

Background: Distinguishing inflammatory bowel disease (IBD) from functional
gastrointestinal (GI) disease remains an important issue for gastroenterologists and primary …

When compared with the general population, patients with coeliac disease (CD) have an
increased risk of developing enteropathy‐associated T‐cell lymphoma (EATCL) …

Patients with coeliac disease have IgM antibodies and IgA anti-gliadin antibody in gut
secretions, and also high counts of intraepithelial lymphocytes (IEL) that express the …

Background: It is well‐recognized that patients with low thiopurine methyltransferase activity
are more susceptible to the development of bone marrow suppression side‐effects. Aim: To …

In this paper we consider recent new data on the pathological features of gluten sensitivity
and on the disease‐associated antigens, in the context of a multistage hypothesis that we …

BACKGROUND: Bile acid malabsorption (BAM) is a recognized cause of watery diarrhea,
often diagnosed empirically based on clinical response to cholestyramine. The radionuclide …

Anti-endomysium antibodies (AEM) fail to identify all untreated celiac disease (CD) patients.
This study aims to determine if additional serology, in particular, IgA anti-tissue …

Background: The faecal enzymes elastase and chymotrypsin are a relatively inexpensive
non-invasive means of investigating causes of malabsorption. However, such tests may be …