Early indicators of prognosis in fulminant hepatic failure

JG O'Grady, GJM Alexander, KM Hayllar, R Williams - Gastroenterology, 1989 - Elsevier
The successful use of orthotopic liver transplantation in fulminant hepatic failure has created
a need for early prognostic indicators to select the patients most likely to benefit at a time …

Natural history and prognostic variables in primary sclerosing cholangitis

JM Farrant, KM Hayllar, ML Wilkinson, J Karani… - Gastroenterology, 1991 - Elsevier
The clinical features at the time of presentation and the outcome in 126 patients with primary
sclerosing cholangitis were studied to clarify the natural history and prognosis in …

Susceptibility to autoimmune chronic active hepatitis: human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors

PT Donaldson, DG Doherty, KM Hayllar… - Hepatology, 1991 - journals.lww.com
After nearly 18 years of research, the association between human leukocyte antigens A1-B8-
DR3 and autoimmune chronic active hepatitis still provokes debate. The principal reasons …

Coagulation factor V and VIII/V ratio as predictors of outcome in paracetamol induced fulminant hepatic failure: relation to other prognostic indicators.

LM Pereira, PG Langley, KM Hayllar, JM Tredger… - Gut, 1992 - gut.bmj.com
The value of coagulation factor V and VIII/V levels as prognostic indicators was assessed in
27 patients with fulminant hepatic failure and compared with other predictive indices …

A prognostic model for the prediction of survival in cystic fibrosis.

KM Hayllar, SG Williams, AE Wise, S Pouria… - Thorax, 1997 - thorax.bmj.com
BACKGROUND: The treatment for endstage cystic fibrosis is, where appropriate, double-
lung, heart-lung or, occasionally, heart-lung-liver transplantation. Optimising the timing of …

[PDF][PDF] Amino acid substitutions at position 38 of the DRβ polypeptide confer susceptibility to and protection from primary sclerosing cholangitis

JM Farrant, DG Doherty, PT Donaldson… - …, 1992 - Wiley Online Library
Previous studies based on serological HLA phenotyping have implicated genes in the HLA
class II region in susceptibility to and protection from primary sclerosing cholangitis. In a …

[PDF][PDF] Centrilobular necrosis after orthotopic liver transplantation: a longitudinal clinicopathologic study in 71 patients

B Turlin, GI Slapak, KM Hayllar… - Liver Transplantation …, 1995 - Wiley Online Library
Centrilobular necrosis (CLN) is a histological finding often encountered after orthotopic liver
transplantation, but its pathogenesis is still unknown. In this study, the significance of CLN …

Use of quantitative liver function tests—caffeine clearance and galactose elimination capacity—after orthotopic liver transplantation

RA Nagel, LY Dirix, KM Hayllar, R Preisig… - Journal of …, 1990 - Elsevier
To establish the potential value of quantitative tests of liver function following orthotopic liver
transplantation (OLT), a total of 100 determinations of caffeine clearance (CafCl) and …

Coagulation factors V and VIII in relation to severity and outcome in acute alcoholic hepatitis

LMMB PEREIRA, PG LANGLEY, GLA BIRD… - Alcohol and …, 1992 - academic.oup.com
The relationship between levels of coagulation Factors V and VIII and disease severity was
evaluated in 33 patients with alcoholic liver disease, and related to outcome in the 23 with …

[CITATION][C] Caffeine Clearance and Galactose Elimination Capacity as Prognostic Indicators in Fulminant Hepatic-Failure

RA Nagel, KM Hayllar, JM Tredger… - European journal of …, 1991 - espace.library.uq.edu.au
Caffeine clearance and galactose elimination capacity were evaluated in parallel on
admission and during the clinical course of 16 patients with fulminant hepatic failure. On …