Compromised CD4+ CD25high regulatory T‐cell function in patients with relapsing‐remitting multiple sclerosis is correlated with a reduced frequency of FOXP3 …
K Venken, N Hellings, M Thewissen, V Somers… - …, 2008 - Wiley Online Library
Summary CD4+ CD25high regulatory T cells (Tregs) of patients with relapsing‐remitting
(RR) multiple sclerosis (MS), in contrast to those of patients with secondary progressive (SP) …
(RR) multiple sclerosis (MS), in contrast to those of patients with secondary progressive (SP) …
Natural naive CD4+ CD25+ CD127low regulatory T cell (Treg) development and function are disturbed in multiple sclerosis patients: recovery of memory Treg …
K Venken, N Hellings, T Broekmans… - The Journal of …, 2008 - journals.aai.org
Patients with relapsing-remitting multiple sclerosis (RR-MS) show a suboptimal CD4+
CD25+ regulatory T cell (Treg) function, whereas no Treg alterations are observed in …
CD25+ regulatory T cell (Treg) function, whereas no Treg alterations are observed in …
Recovery of regional but not global contractile function by the direct intramyocardial autologous bone marrow transplantation: results from a randomized controlled …
M Hendrikx, K Hensen, C Clijsters, H Jongen… - Circulation, 2006 - Am Heart Assoc
Background—Recent trials have shown that intracoronary infusion of bone marrow cells
(BMCs) improves functional recovery after acute myocardial infarction. However, whether …
(BMCs) improves functional recovery after acute myocardial infarction. However, whether …
Secondary progressive in contrast to relapsing‐remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T‐cell function and FOXP3 expression
K Venken, N Hellings, K Hensen… - Journal of …, 2006 - Wiley Online Library
Accumulating evidence indicates an immunosuppressive role for CD4+ CD25+ regulatory T
cells (Tregs) in autoimmune diseases. Although an impaired Treg function in patients with …
cells (Tregs) in autoimmune diseases. Although an impaired Treg function in patients with …
Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling
A De Boeck, P Pauwels, K Hensen, JL Rummens… - Gut, 2013 - gut.bmj.com
Objective Bone marrow-derived mesenchymal stem cells (BM-MSC) migrate to primary
tumours and drive tumour progression. This study aimed to identify the molecular …
tumours and drive tumour progression. This study aimed to identify the molecular …
[HTML][HTML] Transcriptional activation capacity of the novel PLAG family of zinc finger proteins
K Kas, ML Voz, K Hensen, E Meyen… - Journal of Biological …, 1998 - ASBMB
We have isolated and characterized two novel cDNAs encoding C 2 H 2 zinc finger proteins
showing high sequence homology to PLAG1, a protein ectopically activated by promoter …
showing high sequence homology to PLAG1, a protein ectopically activated by promoter …
A CFSE based assay for measuring CD4+ CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses
K Venken, M Thewissen, N Hellings, V Somers… - Journal of …, 2007 - Elsevier
CD4+ CD25+ regulatory T cells (Tregs) are considered to play a key role as suppressors of
immune mediated reactions. The analysis of Treg function in patients with autoimmune …
immune mediated reactions. The analysis of Treg function in patients with autoimmune …
Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11
SF Landrette, YH Kuo, K Hensen… - Blood, 2005 - ashpublications.org
Recurrent chromosomal rearrangements are associated with the development of acute
myeloid leukemia (AML). The frequent inversion of chromosome 16 creates the CBFB …
myeloid leukemia (AML). The frequent inversion of chromosome 16 creates the CBFB …
The tumorigenic diversity of the three PLAG family members is associated with different DNA binding capacities
K Hensen, ICC Van Valckenborgh, K Kas… - Cancer research, 2002 - AACR
Abstract Pleomorphic adenoma gene (PLAG) 1, the main translocation target in pleomorphic
adenomas of the salivary glands, is a member of a new subfamily of zinc finger proteins …
adenomas of the salivary glands, is a member of a new subfamily of zinc finger proteins …
Microarray screening for target genes of the proto-oncogene PLAG1
ML Voz, J Mathys, K Hensen, H Pendeville… - Oncogene, 2004 - nature.com
PLAG1 is a proto-oncogene whose ectopic expression can trigger the development of
pleomorphic adenomas of the salivary glands and of lipoblastomas. As PLAG1 is a …
pleomorphic adenomas of the salivary glands and of lipoblastomas. As PLAG1 is a …