Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling
W Liu, X Dong, M Mai, RS Seelan, K Taniguchi… - Nature …, 2000 - nature.com
1095 (T1) Wt/mut 2083 del G L688X Wt/mut 1–2 1219 (T2)–/mut 2084 ins G E706X–/mut 1
1556 (T3) Wt/mut 2084 ins G E706X Wt/mut 1 2174 (T4) Wt/mut 2084 ins G E706X Wt/mut 1 …
1556 (T3) Wt/mut 2084 ins G E706X Wt/mut 1 2174 (T4) Wt/mut 2084 ins G E706X Wt/mut 1 …
Low-grade dysplasia in Barrett's esophagus: overdiagnosed and underestimated
WL Curvers, FJ Ten Kate, KK Krishnadath… - Official journal of the …, 2010 - journals.lww.com
OBJECTIVES: Published data on the natural history of low-grade dysplasia (LGD) in
Barrett's esophagus (BE) are inconsistent and difficult to interpret. We investigated the …
Barrett's esophagus (BE) are inconsistent and difficult to interpret. We investigated the …
Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel
LC Duits, KN Phoa, WL Curvers, FJW Ten Kate… - Gut, 2015 - gut.bmj.com
Objective Reported malignant progression rates for low-grade dysplasia (LGD) in Barrett's
oesophagus (BO) vary widely. Expert histological review of LGD is advised, but limited data …
oesophagus (BO) vary widely. Expert histological review of LGD is advised, but limited data …
Long-term survival following endoscopic and surgical treatment of high-grade dysplasia in Barrett's esophagus
Background & Aims: Photodynamic therapy (PDT) for high-grade dysplasia (HGD) in
Barrett's esophagus is a Food and Drug Administration–approved alternative to …
Barrett's esophagus is a Food and Drug Administration–approved alternative to …
Detection of residual disease after neoadjuvant chemoradiotherapy for oesophageal cancer (preSANO): a prospective multicentre, diagnostic cohort study
BJ Noordman, MCW Spaander, R Valkema… - The Lancet …, 2018 - thelancet.com
Background After neoadjuvant chemoradiotherapy for oesophageal cancer, roughly half of
the patients with squamous cell carcinoma and a quarter of those with adenocarcinoma …
the patients with squamous cell carcinoma and a quarter of those with adenocarcinoma …
Histologic evaluation of resection specimens obtained at 293 endoscopic resections in Barrett's esophagus
FP Peters, KPM Brakenhoff, WL Curvers… - Gastrointestinal …, 2008 - Elsevier
BACKGROUND: Evidence-based selection criteria for endoscopic resection (ER) of Barrett's
neoplasia are scarce. OBJECTIVE: To study the histopathology of ER specimens of Barrett's …
neoplasia are scarce. OBJECTIVE: To study the histopathology of ER specimens of Barrett's …
Bone morphogenetic protein 4 expressed in esophagitis induces a columnar phenotype in esophageal squamous cells
F Milano, JWPM Van Baal, NS Buttar, AM Rygiel… - Gastroenterology, 2007 - Elsevier
Background & Aims: Barrett's esophagus (BE) is a metaplastic condition in which normal
squamous esophageal epithelium is replaced by columnar epithelium. It is proposed that …
squamous esophageal epithelium is replaced by columnar epithelium. It is proposed that …
Endoscopic treatment of high-grade dysplasia and early stage cancer in Barrett's esophagus
FP Peters, MA Kara, WD Rosmolen… - Gastrointestinal …, 2005 - Elsevier
BACKGROUND: The aim of this study was to prospectively evaluate endoscopic resection
(ER) combined with photodynamic therapy (PDT) for the treatment of selected patients with …
(ER) combined with photodynamic therapy (PDT) for the treatment of selected patients with …
Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
EA Ebbing, AP van der Zalm, A Steins… - Proceedings of the …, 2019 - National Acad Sciences
Esophageal adenocarcinoma (EAC) has a dismal prognosis, and survival benefits of recent
multimodality treatments remain small. Cancer-associated fibroblasts (CAFs) are known to …
multimodality treatments remain small. Cancer-associated fibroblasts (CAFs) are known to …
Stepwise radical endoscopic resection is effective for complete removal of Barrett's esophagus with early neoplasia: a prospective study
FP Peters, MA Kara, WD Rosmolen… - Official journal of the …, 2006 - journals.lww.com
OBJECTIVES Endoscopic therapy for early neoplasia in Barrett's esophagus (BE) is
evolving rapidly. Aim of this study was to prospectively evaluate safety and efficacy of …
evolving rapidly. Aim of this study was to prospectively evaluate safety and efficacy of …