Artificial intelligence for disease assessment in inflammatory bowel disease: how will it change our practice?

RW Stidham, K Takenaka - Gastroenterology, 2022 - Elsevier
Artificial intelligence (AI) has arrived and it will directly impact how we assess, monitor, and
manage inflammatory bowel disease (IBD). Advances in the machine learning …

Development and validation of a deep neural network for accurate evaluation of endoscopic images from patients with ulcerative colitis

K Takenaka, K Ohtsuka, T Fujii, M Negi, K Suzuki… - Gastroenterology, 2020 - Elsevier
Background & Aims There are intra-and interobserver variations in endoscopic assessment
of ulcerative colitis (UC) and biopsies are often collected for histologic evaluation. We …

[HTML][HTML] Tacrolimus for the treatment of ulcerative colitis

K Matsuoka, E Saito, T Fujii, K Takenaka… - Intestinal …, 2015 - ncbi.nlm.nih.gov
Tacrolimus is a calcineurin inhibitor used for the treatment of corticosteroid-refractory
ulcerative colitis (UC). Two randomized controlled trials and a number of retrospective …

Comparison of magnetic resonance and balloon enteroscopic examination of the small intestine in patients with Crohn's disease

K Takenaka, K Ohtsuka, Y Kitazume, M Nagahori… - Gastroenterology, 2014 - Elsevier
Background & Aims Magnetic resonance (MR) enterography is a recommended imaging
technique for detecting intestinal involvement in Crohn's disease (CD). However, the …

Higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease

K Takenaka, A Kawamoto, S Hibiya… - Alimentary …, 2021 - Wiley Online Library
Background Several studies have reported a positive correlation between serum drug
concentrations and endoscopic remission in patients with Crohn's disease. Aim To examine …

Systematic review of artificial intelligence‐based image diagnosis for inflammatory bowel disease

A Kawamoto, K Takenaka, R Okamoto… - Digestive …, 2022 - Wiley Online Library
Objectives Diagnosis of inflammatory bowel diseases (IBD) involves combining clinical,
laboratory, endoscopic, histologic, and radiographic data. Artificial intelligence (AI) is rapidly …

[HTML][HTML] Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties

K Suzuki, T Murano, H Shimizu, G Ito, T Nakata… - Journal of …, 2018 - Springer
Abstract Background Intestinal stem cells (ISCs) play indispensable roles in the
maintenance of homeostasis, and also in the regeneration of the damaged intestinal …

Utility of magnetic resonance enterography for small bowel endoscopic healing in patients with Crohn's disease

K Takenaka, K Ohtsuka, Y Kitazume… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: Small bowel (SB) endoscopic healing has not been well studied in patients
with Crohn's disease (CD). This study aims to evaluate the utility of magnetic resonance …

Small bowel healing detected by endoscopy in patients with Crohn's disease after treatment with antibodies against tumor necrosis factor

K Takenaka, T Fujii, K Suzuki, H Shimizu… - Clinical …, 2020 - Elsevier
Background & Aims It is important to objectively assess Crohn's disease (CD) activity in
patients treated with antibodies against tumor necrosis factor (anti-TNF). Detection of …

Deep neural network for video colonoscopy of ulcerative colitis: a cross-sectional study

K Takenaka, T Fujii, A Kawamoto, K Suzuki… - The Lancet …, 2022 - thelancet.com
Background A combination of endoscopic and histological evaluation is important in the
management of patients with ulcerative colitis. We aimed to adapt our previous deep neural …