[HTML][HTML] Harmonized PD-L1 immunohistochemistry for pulmonary squamous-cell and adenocarcinomas
AH Scheel, M Dietel, LC Heukamp, K Jöhrens… - Modern Pathology, 2016 - Elsevier
Immunohistochemistry of the PD-L1 protein may be predictive for anti-PD-1 and anti-PD-L1
immunotherapy in pulmonary adenocarcinoma and in clinically unselected cohorts of so …
immunotherapy in pulmonary adenocarcinoma and in clinically unselected cohorts of so …
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma
B Lamprecht, K Walter, S Kreher, R Kumar… - Nature medicine, 2010 - nature.com
Mammalian genomes contain many repetitive elements, including long terminal repeats
(LTRs), which have long been suspected to have a role in tumorigenesis. Here we present …
(LTRs), which have long been suspected to have a role in tumorigenesis. Here we present …
[HTML][HTML] Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high …
S Darb-Esfahani, CA Kunze, H Kulbe, J Sehouli… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Aims Antibodies targeting the checkpoint molecules programmed cell death 1 (PD-1) and its
ligand PD-L1 are emerging cancer therapeutics. We systematically investigated PD-1 and …
ligand PD-L1 are emerging cancer therapeutics. We systematically investigated PD-1 and …
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma
S Mathas, M Janz, F Hummel, M Hummel… - Nature …, 2006 - nature.com
B cell differentiation is controlled by a complex network of lineage-restricted transcription
factors. How perturbations to this network alter B cell fate remains poorly understood. Here …
factors. How perturbations to this network alter B cell fate remains poorly understood. Here …
Predictive PD-L1 immunohistochemistry for non-small cell lung cancer: Current state of the art and experiences of the first German harmonization study
AH Scheel, M Dietel, LC Heukamp, K Jöhrens… - Der Pathologe, 2016 - Springer
Background Antibodies against PD-1 and PD-L1 can cause strong and durable anti-tumor
immune responses in non-small cell lung cancer (NSCLC). Immunohistochemistry for PD-L1 …
immune responses in non-small cell lung cancer (NSCLC). Immunohistochemistry for PD-L1 …
Structure-sensitive elastography: on the viscoelastic powerlaw behavior of in vivo human tissue in health and disease
I Sack, K Jöhrens, J Würfel, J Braun - Soft matter, 2013 - pubs.rsc.org
Elastography combines medical imaging with soft tissue mechanics and is used for the
diagnosis of diseases associated with an altered stiffness of affected tissue. Beyond …
diagnosis of diseases associated with an altered stiffness of affected tissue. Beyond …
Tomoelastography by multifrequency wave number recovery from time-harmonic propagating shear waves
Palpation is one of the most sensitive, effective diagnostic practices, motivating the
quantitative and spatially resolved determination of soft tissue elasticity parameters by …
quantitative and spatially resolved determination of soft tissue elasticity parameters by …
[HTML][HTML] The immune contexture of liposarcoma and its clinical implications
A Resag, G Toffanin, I Benešová, L Müller, V Potkrajcic… - Cancers, 2022 - mdpi.com
Simple Summary Liposarcomas (LPS) are malignancies arising from adipose tissue. Based
on the histological appearance, five subtypes are distinguished: well-differentiated LPS …
on the histological appearance, five subtypes are distinguished: well-differentiated LPS …
Elevated NF-κB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas
S Mathas, K Jöhrens, S Joos, A Lietz, F Hummel… - Blood, 2005 - ashpublications.org
Transcription factor nuclear factor kappa B (NF-κB) plays a central role in the pathogenesis
of classical Hodgkin lymphoma (cHL). In anaplastic large-cell lymphomas (ALCLs), which …
of classical Hodgkin lymphoma (cHL). In anaplastic large-cell lymphomas (ALCLs), which …
Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α
B Lamprecht, S Kreher… - Blood, The Journal …, 2008 - ashpublications.org
Abstract The malignant Hodgkin/Reed-Sternberg (HRS) cells of classical Hodgkin
lymphoma (HL) are derived from mature B cells, but have lost a considerable part of the B …
lymphoma (HL) are derived from mature B cells, but have lost a considerable part of the B …