Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence
due to the obesity epidemic. Hence, NAFLD represents a rising threat to public health …

Hyperlipidemia is the most important risk factor for atherosclerosis, which is the major cause
of cardiovascular disease. The etiology of hyperlipidemia and atherosclerosis is complex …

Genome-wide association studies (GWASs) provide an unprecedented opportunity to
examine, on a large scale, the association of common genetic variants with complex …

Nonalcoholic steatohepatitis (NASH) involves liver lipid accumulation (steatosis) combined
with hepatic inflammation. The transition towards hepatic inflammation represents a key step …

Background—Cardiac hypertrophy and subsequent heart failure triggered by chronic
hypertension represent major challenges for cardiovascular research. Beyond …

Aims Rupture-prone atherosclerotic plaques are characterized by inflammation and a large
necrotic core. Inflammation is linked to high metabolic activity. Advanced glycation …

BACKGROUND/AIMS: The molecular mechanisms leading to Non-Alcoholic Steatohepatitis
(NASH) are not fully understood. In mice, NASH can be inhibited by fenofibrate, a synthetic …

Background & Aims Non-alcoholic steatohepatitis (NASH) involves steatosis combined with
inflammation, which can progress into fibrosis and cirrhosis. Exploring the molecular …

BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) is a disorder that consists of
steatosis and hepatic inflammation. It is not known why only some people with steatosis …

Objective Obesity is a risk factor for non-alcoholic steatohepatitis (NASH). This risk has been
attributed to visceral adipose tissue (vAT) expansion associated with increased …