IL-17 and IL-22 have been shown to increase protection against certain bacteria and fungal
pathogens in experimental models. However, no human studies have demonstrated a …

BACKGROUND & AIMS: Polymorphisms in IL28B were shown to affect clearance of
hepatitis C virus (HCV) infection in genome-wide association (GWA) studies. Only a fraction …

In populations exposed to Leishmania braziliensis, certain subjects develop skin ulcers,
whereas others are naturally protected against cutaneous leishmaniasis. We have …

Objective The natural course of chronic hepatitis C varies widely. To improve the profiling of
patients at risk of developing advanced liver disease, we assessed the relative contribution …

In leishmaniasis, Th1-related cytokines production seems to be crucial for host control of
parasite burden and clinical cure. Visceral and diffuse cutaneous leishmaniasis are …

Immunity against schistosomes includes anti‐infection immunity, which is mainly active
against invading larvae in the skin, and anti‐disease immunity, which controls abnormal …

Interleukin (IL)‐22 acts on epithelia, hepatocytes, and pancreatic cells and stimulates innate
immunity, tissue protection, and repair. IL‐22 may also cause inflammation and abnormal …

The MEPE (matrix extracellular phosphoglycoprotein) gene is a strong candidate for the
tumor-derived phosphaturic factor in oncogenic hypophosphatemic osteomalacia (OHO). X …

Schistosome infection is a major public health concern affecting millions of people living in
tropical regions of Africa, Asia, and South America. Schistosomes cause mild clinical …

Millions of humans are exposed to schistosome infections, which cause severe kidney and
liver disease and 280,000 deaths annually. Th2-mediated immunity is critical to human …