User profiles for "author:L M SOLLID"
 | Ludvig M. SollidProfessor of Medicine (Immunology), University of Oslo Verified email at medisin.uio.no Cited by 37876 |
Coeliac disease: dissecting a complex inflammatory disorder
LM Sollid - Nature Reviews Immunology, 2002 - nature.com
The disease mechanisms of complex inflammatory disorders are difficult to define because
of extensive interactions between genetic and environmental factors. Coeliac disease is a …
of extensive interactions between genetic and environmental factors. Coeliac disease is a …
Molecular basis of celiac disease
LM Sollid - Annual review of immunology, 2000 - annualreviews.org
Celiac disease (CD) is an intestinal disorder with multifactorial etiology. HLA and non-HLA
genes together with gluten and possibly additional environmental factors are involved in …
genes together with gluten and possibly additional environmental factors are involved in …
Integration of genetic and immunological insights into a model of celiac disease pathogenesis
Celiac disease (CD) is a gluten-sensitive enteropathy that develops in genetically
susceptible individuals by exposure to cereal gluten proteins. This review integrates insights …
susceptible individuals by exposure to cereal gluten proteins. This review integrates insights …
Structural basis for gluten intolerance in celiac sprue
Celiac Sprue, a widely prevalent autoimmune disease of the small intestine, is induced in
genetically susceptible individuals by exposure to dietary gluten. A 33-mer peptide was …
genetically susceptible individuals by exposure to dietary gluten. A 33-mer peptide was …
Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
The action of tissue Transglutaminase1 (TGase) on specific protein-bound glutamine
residues plays a critical role in numerous biological processes2–5. Here we provide …
residues plays a critical role in numerous biological processes2–5. Here we provide …
Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer.
Typing of DNA from 94 unrelated children with celiac disease (CD) with HLA-DQA1 and-
DQB1 allele-specific oligonucleotide probes revealed that all but one (ie, 98.9%) may share …
DQB1 allele-specific oligonucleotide probes revealed that all but one (ie, 98.9%) may share …
The intestinal T cell response to α-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase
The great majority of patients that are intolerant of wheat gluten protein due to celiac disease
(CD) are human histocompatibility leukocyte antigen (HLA)-DQ2+, and the remaining few …
(CD) are human histocompatibility leukocyte antigen (HLA)-DQ2+, and the remaining few …
HLA types in celiac disease patients not carrying the DQA1* 05-DQB1* 02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease
K Karell, AS Louka, SJ Moodie, H Ascher, F Clot… - Human immunology, 2003 - Elsevier
Genetic susceptibility to celiac disease is strongly associated with HLA-DQA1* 05-DQB1* 02
(DQ2) and HLA-DQA1* 03-DQB1* 0302 (DQ8). Study of the HLA associations in patients not …
(DQ2) and HLA-DQA1* 03-DQB1* 0302 (DQ8). Study of the HLA associations in patients not …
Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease
Background & Aims: Celiac disease appears to be a T cell–mediated enteropathy induced
by gluten in genetically predisposed individuals. Duodenal biopsy specimens from patients …
by gluten in genetically predisposed individuals. Duodenal biopsy specimens from patients …
HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis
The overrepresentation of particular HLA alleles in patients with celiac disease was first
noted two decades ago. Several lines of evidence obtained during the last years strongly …
noted two decades ago. Several lines of evidence obtained during the last years strongly …