During ischemic stroke, neurons at risk are exposed to pathologically high levels of
intracellular calcium (Ca++), initiating a fatal biochemical cascade. To protect these neurons …

Aim—Solid and papillary epithelial neoplasm (SPEN) is an uncommon pancreatic tumour.
Very rarely it has also been described outside the pancreas, usually arising from heterotopic …

3-Aryl-3-fluorooxindoles can be efficiently synthesized in two steps by the addition of an aryl
Grignard to an isatin, followed by treatment with DAST. Oxindole 1 (BMS-204352; …

The morphotype and grade of renal cell carcinoma (RCC) in 928 nephrectomies were
reclassified according to the 2016 WHO classification in order to analyze the distribution and …

Interphase fluorescence in situ hybridization (i‐FISH) is a powerful tool for visualizing
various molecular targets in non‐dividing cells. Manual scoring of i‐FISH signals is a labor …

Compound 8a (BMS-191011), an opener of the cloned large-conductance, Ca2+-activated
potassium (maxi-K) channel, demonstrated efficacy in in vivo stroke models, which led to its …

AIMS: There is increasing evidence that O-linked N-acetylglucosamine (O-GlcNAc) plays an
important role in cell signaling pathways. It has also been reported that increases in O …

Background Recurrent genetic lesions provide basis for risk assessment in pediatric acute
lymphoblastic leukemia (ALL). However, current prognostic classifiers rely on a limited …

The diagnosis of mesenchymal neoplasm by fine‐needle aspiration biopsy (FNAB) has
presented a diagnostic challenge. Most reports claim an accuracy approaching 95%, but …

Integration of viral DNA into the host cell genome is an obligatory process for successful
replication of HIV-1. Integrase catalyzes the insertion of viral DNA into the target DNA and is …