Objectives There is an important need to evaluate therapeutic approaches for osteoarthritis
(OA) in terms of cost-effectiveness as well as efficacy. Methods The ESCEO expert working …

Importance Even though osteoarthritis is a chronic and progressive disease,
pharmacological agents are mainly studied over short-term periods, resulting in unclear …

Objectives Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are common diseases
that frequently co-exist, along with overweight/obesity. While the mechanical impact of …

Background Treatment of osteoarthritis is usually limited to short-term symptom control. We
assessed the effects of the specific drug glucosamine sulphate on the long-term progression …

Background Conventional symptomatic treatments for osteoarthritis do not favorably affect
disease progression. The aim of this randomized, placebo-controlled trial was to determine …

Glucosamine sulfate is able to stimulate proteoglycan synthesis by chondrocytes and has
mild anti-inflammatory properties. In clinical trials, glucosamine sulfate was more effective …

Glucosamine sulfate is a drug used for the treatment of osteoarthritis (OA), based on its
pharmacological and metabolic activities on the cartilage and chondrocytes, complemented …

BACKGROUND AND AIMS The mechanism of intraduodenal fat induced inhibition of food
intake is still unclear. Therefore, we tested the ability of duodenal fatty acids to suppress food …

OBJECTIVE: To assess the incidence of Total Joint Replacement (TJR) during the long-term
follow-up of patients with knee osteoarthritis (OA) formerly receiving treatment with …

Objective: This study investigated thein-vitroeffects of a crystalline glucosamine sulfate (GS)
preparation on DNA synthesis and on proteoglycan (PG) and type II collagen (coll II) …