User profiles for "author:Luca Miele"

Luca Miele

Fondazione Pol. Univ. A. Gemelli IRCCS, Universitą Cattolica Sacro Cuore. Roma
Verified email at policlinicogemelli.it
Cited by 14111

[HTML][HTML] Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: a systematic review and meta-analysis

EA Selvaraj, FE Mózes, ANA Jayaswal… - Journal of …, 2021 - Elsevier
Background and Aims Vibration-controlled transient elastography (VCTE), point shear wave
elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic …

Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups

A Lonardo, S Bellentani, CK Argo, S Ballestri… - Digestive and Liver …, 2015 - Elsevier
An improved understanding of non-alcoholic fatty liver disease epidemiology would lead to
identification of individuals at high risk of developing chronic liver disease and extra-hepatic …

AISF position paper on nonalcoholic fatty liver disease (NAFLD): Updates and future directions

A Lonardo, F Nascimbeni, G Targher… - Digestive and Liver …, 2017 - Elsevier
This review summarizes our current understanding of nonalcoholic fatty liver disease
(NAFLD), a multi-factorial systemic disease resulting from a complex interaction between a …

[PDF][PDF] Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

L Miele, V Valenza, G La Torre, M Montalto… - …, 2009 - Wiley Online Library
The role played by the gut in nonalcoholic fatty liver disease (NAFLD) is still a matter of
debate, although animal and human studies suggest that gut‐derived endotoxin may be …

[HTML][HTML] Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores

C Bianco, O Jamialahmadi, S Pelusi, G Baselli… - Journal of …, 2021 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) risk stratification in individuals with
dysmetabolism is a major unmet need. Genetic predisposition contributes to non-alcoholic …

The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota

ML Balmer, E Slack, A De Gottardi… - Science translational …, 2014 - science.org
A prerequisite for establishment of mutualism between the host and the microbial community
that inhabits the large intestine is the stringent mucosal compartmentalization of …

[HTML][HTML] MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals

B Donati, P Dongiovanni, S Romeo, M Meroni… - Scientific reports, 2017 - nature.com
Nonalcoholic fatty liver disease (NAFLD) represents an emerging cause of hepatocellular
carcinoma (HCC), especially in non-cirrhotic individuals. The rs641738 C> T …

Prognostic factors for survival in patients with early-intermediate hepatocellular carcinoma undergoing non-surgical therapy: comparison of Okuda, CLIP, and BCLC …

A Grieco, M Pompili, G Caminiti, L Miele, M Covino… - Gut, 2005 - gut.bmj.com
Background: Several prognostic models have been developed to stage hepatocellular
carcinoma (HCC) but there is no general consensus on which is the most reliable. We …

NAFLD in children: new genes, new diagnostic modalities and new drugs

V Nobili, A Alisi, L Valenti, L Miele… - Nature reviews …, 2019 - nature.com
Nonalcoholic fatty liver disease (NAFLD) has rapidly become the most common form of
chronic liver disease in children and adolescents. Over the past 5 years, developments have …

Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial

C Loguercio, P Andreone, C Brisc, MC Brisc… - Free Radical Biology …, 2012 - Elsevier
The only currently recommended treatment for nonalcoholic fatty liver disease (NAFLD) is
lifestyle modification. Preliminary studies of silybin showed beneficial effects on liver …