A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the …

CR Boland, SN Thibodeau, SR Hamilton, D Sidransky… - Cancer research, 1998 - AACR
Abstract In December 1997, the National Cancer Institute sponsored “The International
Workshop on Microsatellite Instability and RER Phenotypes in Cancer Detection and …

Lymph node evaluation and survival after curative resection of colon cancer: systematic review

GJ Chang, MA Rodriguez-Bigas… - Journal of the …, 2007 - academic.oup.com
Background Adequate lymph node evaluation for cancer involvement is important for
prognosis and treatment of patients with colon cancer. The number of lymph nodes …

ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes

JG Guillem, WC Wood, JF Moley, A Berchuck… - Annals of surgical …, 2006 - Springer
Background A significant portion of cancers are accounted for by a heritable component,
which has increasingly been linked to mutations in specific genes. Clinical interventions …

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

A Umar, CR Boland, JP Terdiman… - Journal of the …, 2004 - academic.oup.com
Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is a
common autosomal dominant syndrome characterized by early age at onset, neoplastic …

[HTML][HTML] The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

G Steinbach, PM Lynch, RKS Phillips… - … England Journal of …, 2000 - Mass Medical Soc
Background Patients with familial adenomatous polyposis have a nearly 100 percent risk of
colorectal cancer. In this disease, the chemopreventive effects of nonsteroidal …

A National Cancer Institute workshop on hereditary nonpolyposis colorectal cancer syndrome: meeting highlights and Bethesda guidelines

MA Rodriguez-Bigas, CR Boland… - Journal of the …, 1997 - academic.oup.com
Hereditary nonpolyposis colorectal cancer (HNPCC) is a distinct autosomal dominant
syndrome accounting for approximately 5%–6% of the total colorectal cancer burden with …

Increasing disparities in the age-related incidences of colon and rectal cancers in the United States, 1975-2010

CE Bailey, CY Hu, YN You, BK Bednarski… - JAMA …, 2015 - jamanetwork.com
Importance The overall incidence of colorectal cancer (CRC) has been decreasing since
1998 but there has been an apparent increase in the incidence of CRC in young adults …

[HTML][HTML] Neoadjuvant treatment response as an early response indicator for patients with rectal cancer

IJ Park, YN You, A Agarwal, JM Skibber… - Journal of clinical …, 2012 - ncbi.nlm.nih.gov
Purpose Neoadjuvant chemoradiotherapy for rectal cancer is associated with improved local
control and may result in complete tumor response. Associations between tumor response …

Predictors of tumor response and downstaging in patients who receive preoperative chemoradiation for rectal cancer

P Das, JM Skibber, MA Rodriguez‐Bigas, BW Feig… - Cancer, 2007 - Wiley Online Library
BACKGROUND The objective of this study was to identify predictive factors for pathologic
complete response and tumor downstaging after preoperative chemoradiation for rectal …

The onset and extent of genomic instability in sporadic colorectal tumor progression

DL Stoler, N Chen, M Basik… - Proceedings of the …, 1999 - National Acad Sciences
Cancer cell genomes contain alterations beyond known etiologic events, but their total
number has been unknown at even the order of magnitude level. By sampling colorectal …