[HTML][HTML] Chlorhexidine–alcohol versus povidone–iodine for surgical-site antisepsis

RO Darouiche, MJ Wall Jr, KMF Itani… - … England Journal of …, 2010 - Mass Medical Soc
Background Since the patient's skin is a major source of pathogens that cause surgical-site
infection, optimization of preoperative skin antisepsis may decrease postoperative …

Impact of Clostridium difficile on inflammatory bowel disease

M Issa, A Vijayapal, MB Graham, DB Beaulieu… - Clinical …, 2007 - Elsevier
Background & Aims: Clostridium difficile–associated disease has increased significantly in
North American medical centers. The impact of C difficile on patients with IBD (Crohn's …

[HTML][HTML] Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2

J Heidemann, H Ogawa, MB Dwinell, P Rafiee… - Journal of Biological …, 2003 - ASBMB
Angiogenesis plays a critical role in metastasis and tumor growth. Human tumors, including
colorectal adenocarcinoma, secrete angiogenic factors, inducing proliferation and …

Animal models for medical countermeasures to radiation exposure

JP Williams, SL Brown, GE Georges… - Radiation …, 2010 - meridian.allenpress.com
Abstract Since September 11, 2001, there has been the recognition of a plausible threat
from acts of terrorism, including radiological or nuclear attacks. A network of Centers for …

Acquired microvascular dysfunction in inflammatory bowel disease: loss of nitric oxide-mediated vasodilation

OA Hatoum, DG Binion, MF Otterson, DD Gutterman - Gastroenterology, 2003 - Elsevier
BACKGROUND & AIMS:: Inflammatory bowel disease (IBD; ie, Crohn's disease, ulcerative
colitis) is characterized by refractory inflammatory ulceration and damage to the intestine …

Small intestinal physiology and pathophysiology

SK Sarna, MF Otterson - Gastroenterology Clinics of North America, 1989 - Elsevier
The small intestine, like the rest of the gastrointestinal tract, is an intelligent organ. It
generates a wide variety of motor patterns to meet motility requirements in different …

Normal physiology of small intestinal motility

MF Otterson, MG Sarr - Surgical Clinics of North America, 1993 - Elsevier
The small intestine produces a number of different contractions in various spatial and
temporal patterns that promote efficient digestion, absorption, and propulsion of ingested …

Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition

DG Binion, MF Otterson, P Rafiee - Gut, 2008 - gut.bmj.com
Background: Angiogenesis, the growth of new blood vessels, is a critical homeostatic
mechanism which regulates vascular populations in response to physiological requirements …

Severe pulmonary toxicity after azathioprine/6-mercaptopurine initiation for the treatment of inflammatory bowel disease

AN Ananthakrishnan, T Attila, MF Otterson… - Journal of clinical …, 2007 - journals.lww.com
Abstract Azathioprine and 6-mercaptopurine (6-MP) are effective in inflammatory bowel
disease (IBD). However, between 10% and 29% of patients treated with these drugs are …

Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease

S Horowitz, DG Binion, VM Nelson… - American journal …, 2007 - journals.physiology.org
Nitric oxide (· NO) generation from conversion of l-arginine to citrulline by nitric oxide
synthase isoforms plays a critical role in vascular homeostasis. Loss of· NO is linked to …