Hereditary diffuse gastric cancer: updated clinical practice guidelines
VR Blair, M McLeod, F Carneiro, DG Coit… - The Lancet …, 2020 - thelancet.com
Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome that is
characterised by a high prevalence of diffuse gastric cancer and lobular breast cancer. It is …
characterised by a high prevalence of diffuse gastric cancer and lobular breast cancer. It is …
[HTML][HTML] Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment
T Aparicio, A Zaanan, M Svrcek, P Laurent-Puig… - Digestive and liver …, 2014 - Elsevier
Small bowel adenocarcinomas are rare tumours, but their incidence is increasing. Their
most common primary location is the duodenum. The few studies that have collected data …
most common primary location is the duodenum. The few studies that have collected data …
[HTML][HTML] Deficient mismatch repair/microsatellite unstable colorectal cancer: Diagnosis, prognosis and treatment
Microsatellite unstable (MSI) colorectal cancers (CRCs) are due to DNA mismatch repair
(MMR) deficiency and occurs in15% of non-metastatic diseases and 5% in the metastatic …
(MMR) deficiency and occurs in15% of non-metastatic diseases and 5% in the metastatic …
Stratification of pancreatic ductal adenocarcinomas based on tumor and microenvironment features
Background & Aims Genomic studies have revealed subtypes of pancreatic ductal
adenocarcinoma (PDA) based on their molecular features, but different studies have …
adenocarcinoma (PDA) based on their molecular features, but different studies have …
Risk of colorectal high-grade dysplasia and cancer in a prospective observational cohort of patients with inflammatory bowel disease
L Beaugerie, M Svrcek, P Seksik, AM Bouvier, T Simon… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: There is an unclear risk of colonic high-grade dysplasia (HGD) and
colorectal cancer (CRC) among patients with inflammatory bowel disease (IBD) treated with …
colorectal cancer (CRC) among patients with inflammatory bowel disease (IBD) treated with …
Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma
BACKGROUND & AIMS: Patients who undergo surgery for pancreatic ductal
adenocarcinoma (PDAC) frequently receive adjuvant gemcitabine chemotherapy. Key …
adenocarcinoma (PDAC) frequently receive adjuvant gemcitabine chemotherapy. Key …
[HTML][HTML] Neoadjuvant nivolumab plus ipilimumab and adjuvant nivolumab in localized deficient mismatch repair/microsatellite instability–high gastric or …
PURPOSE In patients with resectable gastric/gastroesophageal junction (GEJ)
adenocarcinoma, surgery plus perioperative platinum-based chemotherapy is the standard …
adenocarcinoma, surgery plus perioperative platinum-based chemotherapy is the standard …
Association of primary resistance to immune checkpoint inhibitors in metastatic colorectal cancer with misdiagnosis of microsatellite instability or mismatch repair …
R Cohen, E Hain, O Buhard, A Guilloux… - JAMA …, 2019 - jamanetwork.com
Importance Primary resistance to immune checkpoint inhibitors is observed in 10% to 40%
of patients with metastatic colorectal cancer (mCRC) displaying microsatellite instability …
of patients with metastatic colorectal cancer (mCRC) displaying microsatellite instability …
[HTML][HTML] Prognostic and predictive value of the Immunoscore in stage III colon cancer patients treated with oxaliplatin in the prospective IDEA France PRODIGE …
Background The Immunoscore (IS), which prognostically classifies stage I–III colon cancer
(CC) patients, was evaluated in the International Duration Evaluation of Adjuvant Therapy …
(CC) patients, was evaluated in the International Duration Evaluation of Adjuvant Therapy …
ECCO position paper: harmonization of the approach to ulcerative colitis histopathology
Currently, the main targets of drug therapy for ulcerative colitis [UC] are endoscopic and
clinical remission. However, there is active discussion about the additional advantages of …
clinical remission. However, there is active discussion about the additional advantages of …