Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis

R Moucari, T Asselah, D Cazals–Hatem, H Voitot… - Gastroenterology, 2008 - Elsevier
BACKGROUND & AIMS: Our study was designed to test the association between insulin
resistance (IR) and hepatitis C virus (HCV) genotypes using serum HCV RNA level and liver …

[PDF][PDF] Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa‐2a in HBeAg‐negative patients

R Moucari, V Mackiewicz, O Lada, MP Ripault… - …, 2009 - Wiley Online Library
Pegylated interferon alfa‐2a (PEG‐IFN) may induce sustained virological response (SVR) in
20% of hepatitis B e antigen (HBeAg)‐negative chronic hepatitis B (CHB) patients. In …

Eradication of hepatitis C virus in patients successfully treated for chronic hepatitis C

S Maylin, M Martinot–Peignoux, R Moucari, N Boyer… - Gastroenterology, 2008 - Elsevier
Background & Aims: It is unclear whether hepatitis C virus (HCV) is eradicated in patients
with chronic hepatitis C who achieved a sustained virologic response (SVR). Methods: In …

Impact of peginterferon and ribavirin therapy on hepatocellular carcinoma: incidence and survival in hepatitis C patients with advanced fibrosis

AC Cardoso, R Moucari, C Figueiredo-Mendes… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) currently represents the major
cause of liver-related death in patients with hepatitis C virus (HCV)-related cirrhosis. We …

[PDF][PDF] Efficacy of peginterferon alpha‐2b in chronic hepatitis delta: relevance of quantitative RT‐PCR for follow‐up

C Castelnau, F Le Gal, MP Ripault, E Gordien… - …, 2006 - Wiley Online Library
Hepatitis delta virus (HDV) can cause severe acute and chronic liver disease in patients
infected by hepatitis B virus. Interferon alpha at high doses, although poorly efficient, is the …

[HTML][HTML] Eighth major clade for hepatitis delta virus

F Le Gal, E Gault, MP Ripault, J Serpaggi… - Emerging infectious …, 2006 - ncbi.nlm.nih.gov
Hepatitis delta virus is the only representative of the Deltavirus genus, which consists of 7
differentiated major clades. In this study, an eighth clade was identified from 3 distinct …

IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C

T Asselah, S De Muynck, P Broët… - Journal of …, 2012 - Elsevier
BACKGROUND & AIMS: Polymorphisms in the region of the interleukin (IL) 28B gene have
been associated with pegylated-interferon (PEG-IFN) and ribavirin treatment response …

[PDF][PDF] Twelve weeks posttreatment follow‐up is as relevant as 24 weeks to determine the sustained virologic response in patients with hepatitis C virus receiving …

M Martinot‐Peignoux, C Stern, S Maylin… - …, 2010 - Wiley Online Library
A sustained virologic response (SVR) in patients with chronic hepatitis C receiving
pegylated interferon (PEG‐IFN) plus ribavirin is defined as undetectable serum HCV‐RNA at …

Direct comparison of diagnostic performance of transient elastography in patients with chronic hepatitis B and chronic hepatitis C

AC Cardoso, RJ Carvalho‐Filho, C Stern… - Liver …, 2012 - Wiley Online Library
Abstract Background/Aims Accuracy of transient elastography (TE) in hepatitis B virus (HBV)
infection has not been well established. We aimed to compare the performances of TE for …

Liver gene expression signature to predict response to pegylated interferon plus ribavirin combination therapy in patients with chronic hepatitis C

T Asselah, I Bieche, S Narguet, A Sabbagh… - Gut, 2008 - gut.bmj.com
Background and Aims: The gold standard treatment of chronic hepatitis C (CHC) is
combined pegylated interferon and ribavirin. Considering side effects and treatment cost …