User profiles for "author:Mark A Valasek"
Mark A ValasekProfessor of Pathology, University of California San Diego Verified email at ucsd.edu Cited by 11010 |
The power of real-time PCR
MA Valasek, JJ Repa - Advances in physiology education, 2005 - journals.physiology.org
In recent years, real-time polymerase chain reaction (PCR) has emerged as a robust and
widely used methodology for biological investigation because it can detect and quantify very …
widely used methodology for biological investigation because it can detect and quantify very …
An update on the diagnosis, grading, and staging of appendiceal mucinous neoplasms
MA Valasek, RK Pai - Advances in anatomic pathology, 2018 - journals.lww.com
Despite advances in our understanding of appendiceal mucinous neoplasms and their
relationship to the pseudomyxoma peritonei syndrome, the classification of mucinous tumors …
relationship to the pseudomyxoma peritonei syndrome, the classification of mucinous tumors …
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41
Y Xiong, N Miyamoto, K Shibata… - Proceedings of the …, 2004 - National Acad Sciences
Leptin is an adipose-derived hormone that regulates a wide variety of physiological
processes, including feeding behavior, metabolic rate, sympathetic nerve activity …
processes, including feeding behavior, metabolic rate, sympathetic nerve activity …
Magnetic resonance elastography vs transient elastography in detection of fibrosis and noninvasive measurement of steatosis in patients with biopsy-proven …
CC Park, P Nguyen, C Hernandez, R Bettencourt… - Gastroenterology, 2017 - Elsevier
Background & Aims Magnetic resonance imaging (MRI) techniques and ultrasound-based
transient elastography (TE) can be used in noninvasive diagnosis of fibrosis and steatosis in …
transient elastography (TE) can be used in noninvasive diagnosis of fibrosis and steatosis in …
[PDF][PDF] ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development
H Nakagawa, A Umemura, K Taniguchi… - Cancer cell, 2014 - cell.com
Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of viral
hepatitis, insulin resistance, hepatosteatosis, and nonalcoholic steatohepatitis (NASH) …
hepatitis, insulin resistance, hepatosteatosis, and nonalcoholic steatohepatitis (NASH) …
[PDF][PDF] Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer
Compensatory proliferation triggered by hepatocyte loss is required for liver regeneration
and maintenance but also promotes development of hepatocellular carcinoma (HCC) …
and maintenance but also promotes development of hepatocellular carcinoma (HCC) …
[PDF][PDF] p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells
Summary p62 is a ubiquitin-binding autophagy receptor and signaling protein that
accumulates in premalignant liver diseases and most hepatocellular carcinomas (HCCs) …
accumulates in premalignant liver diseases and most hepatocellular carcinomas (HCCs) …
Development and validation of a histological index for UC
Objective Although the Geboes score (GS) and modified Riley score (MRS) are commonly
used to evaluate histological disease activity in UC, their operating properties are unknown …
used to evaluate histological disease activity in UC, their operating properties are unknown …
[PDF][PDF] Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a …
Ezetimibe inhibits intestinal cholesterol absorption and lowers low‐density lipoprotein
cholesterol. Uncontrolled studies have suggested that it reduces liver fat as estimated by …
cholesterol. Uncontrolled studies have suggested that it reduces liver fat as estimated by …
Histopathology scoring systems of stenosis associated with small bowel Crohn's disease: a systematic review
IO Gordon, D Bettenworth, A Bokemeyer, A Srivastava… - Gastroenterology, 2020 - Elsevier
Background & Aims Stenosis is a common complication of Crohn's disease (CD) that has no
effective medical therapy. Development of antifibrotic agents will require testing in …
effective medical therapy. Development of antifibrotic agents will require testing in …