Summary Background Phase I/II clinical trials of S-1 plus cisplatin for advanced gastric
cancer have yielded good responses and the treatment was well tolerated. In this S-1 Plus …

MANY cytokines signal through different cell-surface receptors to activate the transcription
factor NF-κB (ref. 1). Members of the TRAF protein family have been implicated in the …

In a longitudinal clinical study to compare two groups, the primary end point is often the time
to a specific event (eg, disease progression, death). The hazard ratio estimate is routinely …

Various accumulating evidence suggests that survivin, a member of the inhibitor of
apoptosis (IAP) family, plays an important role in drug resistance and cancer cell survival in …

The two cell surface receptors for tumor necrosis factor (TNF) interact with a number of
intracellular signal transducing proteins. The association of TRADD, a 34-kDa cytoplasmic …

The tumor necrosis factor (TNF) receptor-associated factor (TRAF) family of proteins interact
with and transduce signals for members of the TNF receptor superfamily. TRAF1, TRAF2 …

Fission yeast temperature‐sensitive mutants cut3‐477 and cut14‐208 fail to condense
chromosomes but small portions of the chromosomes can separate along the spindle during …

PURPOSE S-1 is a standard postoperative adjuvant chemotherapy for patients with stage II
or III gastric cancer in Asia. Neoadjuvant or perioperative strategies dominate in Western …

METHODS—The randomized, multicenter, double-blind, placebocontrolled trial was
performed in patients aged from 30 to 74 years with type 2 diabetes and urinary albumin-to …

Background The present study aimed to determine the ability of the revised International
Association for the Study of Lung Cancer (IASLC)/American Thoracic Society …