User profiles for "author:Masaru Morita"

Masaru Morita

MD
Verified email at surg2.med.kyushu-u.ac.jp
Cited by 10016

Deregulation of the Akt pathway in human cancer

E Tokunaga, E Oki, A Egashira… - Current cancer drug …, 2008 - ingentaconnect.com
Akt (protein kinase B) is a serine/threonine kinase which is a central regulator of widely
divergent cellular processes including proliferation, differentiation, migration, survival and …

Activation of PI3K/Akt signaling and hormone resistance in breast cancer

E Tokunaga, Y Kimura, K Mashino, E Oki, A Kataoka… - Breast cancer, 2006 - Springer
Akt is a serine/threonine kinase that has been demonstrated to play an important role in
survival when cells are exposed to different apoptotic stimuli. Recent studies show that …

Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention

M Morita, R Kumashiro, N Kubo, Y Nakashima… - International journal of …, 2010 - Springer
Both cigarette smoking and alcohol drinking are well-established risk factors for esophageal
squamous cell carcinoma (ESCC), and the relationship of dose to cancer risk has already …

Colorectal cancer screening with odour material by canine scent detection

H Sonoda, S Kohnoe, T Yamazato, Y Satoh… - Gut, 2011 - gut.bmj.com
Objective Early detection and early treatment are of vital importance to the successful
treatment of various cancers. The development of a novel screening method that is as …

[HTML][HTML] Comprehensive registry of esophageal cancer in Japan, 2015

M Watanabe, Y Toh, R Ishihara, K Kono, H Matsubara… - Esophagus, 2023 - Springer
Background The registration committee for esophageal cancer in the Japan Esophageal
Society (JES) has collected the patients' characteristics, treatment, and outcomes of patients …

Advances in esophageal cancer surgery in Japan: an analysis of 1000 consecutive patients treated at a single institute

M Morita, R Yoshida, K Ikeda, A Egashira, E Oki… - Surgery, 2008 - Elsevier
BACKGROUND: In Japan, most esophageal cancers are squamous cell carcinomas, and
the results of esophagectomy have improved remarkably in recent years. The object of this …

Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: molecular mechanisms of carcinogenesis

Y Toh, E Oki, K Ohgaki, Y Sakamoto, S Ito… - International journal of …, 2010 - Springer
Esophageal cancer is the eighth most common incident cancer in the world and ranks sixth
among all cancers in mortality. Esophageal cancers are classified into two histological types; …

Role of tumor-associated macrophages in the progression of hepatocellular carcinoma

K Shirabe, Y Mano, J Muto, R Matono, T Motomura… - Surgery today, 2012 - Springer
Recent studies have shown that the tumor microenvironment plays an important role in
cancer progression. Tumor-associated macrophages (TAMs), in particular, have been found …

Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance

H Uramoto, K Sugio, T Oyama, S Nakata, K Ono… - Lung Cancer, 2005 - Elsevier
All eukaryotic cells respond to the accumulation of unfolded proteins in the endoplasmic
reticulum (ER) by signaling an adaptive pathway termed the unfolded protein response …

Modeling of conjunctive two-dimensional surface-three-dimensional subsurface flows

M Morita, BC Yen - Journal of Hydraulic Engineering, 2002 - ascelibrary.org
In the rainfall-runoff process, interaction between surface and subsurface flow components
plays an important role, especially in rainwater abstraction and overland flow initiation at the …