User profiles for "author:Matthieu Rouleau"

Matthieu Rouleau

INSERM, CNRS, Université Côte d'Azur
Verified email at univ-cotedazur.fr
Cited by 8416

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

H Groux, A O'Garra, M Bigler, M Rouleau, S Antonenko… - Nature, 1997 - nature.com
Induction and maintenance of peripheral tolerance are important mechanisms to maintain
the balance of the immune system. In addition to the deletion of T cells and their failure to …

Gut microbiome and bone

L Ibáñez, M Rouleau, A Wakkach, C Blin-Wakkach - Joint Bone Spine, 2019 - Elsevier
The gut microbiome is now viewed as a tissue that interacts bidirectionally with the
gastrointestinal, immune, endocrine and nervous systems, affecting the cellular responses in …

[PDF][PDF] Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells

A Moussaieff, M Rouleau, D Kitsberg, M Cohen, G Levy… - Cell metabolism, 2015 - cell.com
Loss of pluripotency is a gradual event whose initiating factors are largely unknown. Here
we report the earliest metabolic changes induced during the first hours of differentiation …

A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells

H Groux, F Cottrez, M Rouleau, S Mauze… - The Journal of …, 1999 - journals.aai.org
IL-10 is a cytokine secreted by a wide variety of cells type that has pleiotropic stimulatory
and suppressive activities on both lymphoid and myeloid cells in vitro. To analyze the …

microRNA-34a regulates neurite outgrowth, spinal morphology, and function

M Agostini, P Tucci, JR Steinert… - Proceedings of the …, 2011 - National Acad Sciences
The p53 family member TAp73 is a transcription factor that plays a key role in many
biological processes, including neuronal development. In particular, we have shown that …

[PDF][PDF] Reconstituted skin from murine embryonic stem cells

C Coraux, C Hilmi, M Rouleau, A Spadafora… - Current Biology, 2003 - cell.com
Embryonic stem (ES) cell lines can be expanded indefinitely in culture while maintaining
their potential to differentiate into any cell type [1, 2]. During embryonic development, the …

[HTML][HTML] Safety and cross-variant immunogenicity of a three-dose COVID-19 mRNA vaccine regimen in kidney transplant recipients

F Massa, M Cremoni, A Gérard, H Grabsi, L Rogier… - …, 2021 - thelancet.com
Background The immunogenicity of a two-dose mRNA COVID-19 vaccine regimen is low in
kidney transplant (KT) recipients. Here, we provide a thorough assessment of the …

Hypoxic enlarged mitochondria protect cancer cells from apoptotic stimuli

J Chiche, M Rouleau, P Gounon… - Journal of cellular …, 2010 - Wiley Online Library
It is well established that cells exposed to the limiting oxygen microenvironment (hypoxia) of
tumors acquire resistance to chemotherapy, through mechanisms not fully understood. We …

Bone marrow Th17 TNFα cells induce osteoclast differentiation, and link bone destruction to IBD

T Ciucci, L Ibáñez, A Boucoiran, E Birgy-Barelli, J Pène… - Gut, 2015 - gut.bmj.com
Objective Under both physiological and pathological conditions, bone volume is determined
by the rate of bone formation by osteoblasts and bone resorption by osteoclasts. Excessive …

Key role of p63 in BMP-4-induced epidermal commitment of embryonic stem cells

D Aberdam, K Gambaro, P Rostagno, E Aberdam… - Cell cycle, 2007 - Taylor & Francis
In vivo studies, transgenic and knock-out mice have demonstrated that p63 isoforms play
pivotal roles in ectodermal and epidermal development but their respective function remains …