Introduction Microscopic colitis is a chronic inflammatory bowel disease characterised by
normal or almost normal endoscopic appearance of the colon, chronic watery, nonbloody …

The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

The influence of genetics in the etiology of inflammatory bowel disease (IBD) was initially
demonstrated by epidemiological data, including differences in prevalence among different …

Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …

We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …

Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …

To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …

Inflammatory bowel disease (IBD) is characterized by flares of inflammation with a periodic
need for increased medication and sometimes even surgery. The aetiology of IBD is partly …

More than 1,000 susceptibility loci have been identified through genome-wide association
studies (GWAS) of common variants; however, the specific genes and full allelic spectrum of …

Ulcerative colitis is a chronic, relapsing inflammatory condition of the gastrointestinal tract
with a complex genetic and environmental etiology. In an effort to identify genetic variation …