User profiles for "author:Michael A Newton"
Michael A NewtonProfessor of Statistics and of Biostatistics and Medical Informatics, University of Wisconsin Verified email at wisc.edu Cited by 18023 |
Approximate Bayesian inference with the weighted likelihood bootstrap
MA Newton, AE Raftery - Journal of the Royal Statistical Society …, 1994 - academic.oup.com
We introduce the weighted likelihood bootstrap (WLB) as a way to simulate approximately
from a posterior distribution. This method is often easy to implement, requiring only an …
from a posterior distribution. This method is often easy to implement, requiring only an …
Essential hypertension: renin and aldosterone, heart attack and stroke
HR Brunner, JH Laragh, L Baer… - … England Journal of …, 1972 - Mass Medical Soc
In 219 patients with essential hypertension, aldosterone excretion and plasma renin activity
were related to daily sodium excretion and compared to a nomogram drawn from 52 normal …
were related to daily sodium excretion and compared to a nomogram drawn from 52 normal …
On differential variability of expression ratios: improving statistical inference about gene expression changes from microarray data
MA Newton, CM Kendziorski, CS Richmond… - Journal of …, 2001 - liebertpub.com
We consider the problem of inferring fold changes in gene expression from cDNA microarray
data. Standard procedures focus on the ratio of measured fluorescent intensities at each …
data. Standard procedures focus on the ratio of measured fluorescent intensities at each …
Detecting differential gene expression with a semiparametric hierarchical mixture method
Mixture modeling provides an effective approach to the differential expression problem in
microarray data analysis. Methods based on fully parametric mixture models are available …
microarray data analysis. Methods based on fully parametric mixture models are available …
Bayesian phylogenetic inference via Markov chain Monte Carlo methods
We derive a Markov chain to sample from the posterior distribution for a phylogenetic tree
given sequence information from the corresponding set of organisms, a stochastic model for …
given sequence information from the corresponding set of organisms, a stochastic model for …
MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins
S Sengupta, JA den Boon, IH Chen… - Proceedings of the …, 2008 - National Acad Sciences
Using highly sensitive microarray-based procedures, we identified eight microRNAs
(miRNAs) showing robust differential expression between 31 laser-capture-microdissected …
(miRNAs) showing robust differential expression between 31 laser-capture-microdissected …
[HTML][HTML] Drosophila RNAi screen identifies host genes important for influenza virus replication
L Hao, A Sakurai, T Watanabe, E Sorensen, CA Nidom… - Nature, 2008 - nature.com
All viruses rely on host cell proteins and their associated mechanisms to complete the viral
life cycle. Identifying the host molecules that participate in each step of virus replication …
life cycle. Identifying the host molecules that participate in each step of virus replication …
Fundamental differences in cell cycle deregulation in human papillomavirus–positive and human papillomavirus–negative head/neck and cervical cancers
Human papillomaviruses (HPV) are associated with nearly all cervical cancers, 20% to 30%
of head and neck cancers (HNC), and other cancers. Because HNCs also arise in HPV …
of head and neck cancers (HNC), and other cancers. Because HNCs also arise in HPV …
Estimating the integrated likelihood via posterior simulation using the harmonic mean identity
The integrated likelihood (also called the marginal likelihood or the normalizing constant) is
a central quantity in Bayesian model selection and model averaging. It is defined as the …
a central quantity in Bayesian model selection and model averaging. It is defined as the …
Karyotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells
SM Taapken, BS Nisler, MA Newton… - Nature …, 2011 - nature.com
To the Editor: Although induced pluripotent stem cells (iPSCs) resemble embryonic stem
cells (ESCs) with regard to pluripotency1, 2, reports of transcriptional, epigenetic and …
cells (ESCs) with regard to pluripotency1, 2, reports of transcriptional, epigenetic and …