The folding of an enzyme: II. Substructure of barnase and the contribution of different interactions to protein stability

L Serrano, JT Kellis Jr, P Cann, A Matouschek… - Journal of molecular …, 1992 - Elsevier
Barnase is described anatomically in terms of its substructures and their mode of packing.
The surface area of hydrophobic residues buried on formation and packing of the structural …

The relationship between the angle of version and rate of wear of retrieved metal-on-metal resurfacings: a prospective, CT-based study

AJ Hart, K Ilo, R Underwood, P Cann… - The Journal of Bone …, 2011 - boneandjoint.org.uk
We measured the orientation of the acetabular and femoral components in 45 patients (33
men, 12 women) with a mean age of 53.4 years (30 to 74) who had undergone revision of …

An analysis of the mechanisms of grease lubrication in rolling element bearings

P Cann, AA Lubrecht - Lubrication Science, 1999 - Wiley Online Library
There are over eighteen billion bearings in use in the world, and most are grease lubricated.
Grease is chosen for a variety of reasons: it gives low friction, is easily confined, and has a …

Irritable bowel syndrome: relationship of disorders in the transit of a single solid meal to symptom patterns.

PA Cann, NW Read, C Brown, N Hobson… - Gut, 1983 - gut.bmj.com
The time taken for a solid meal to pass through the stomach, small intestine, and colon was
measured in 61 patients with irritable bowel syndrome, subdivided according to their …

British Society of Gastroenterology guidelines for the management of the irritable bowel syndrome

J Jones, J Boorman, P Cann, A Forbes, J Gomborone… - Gut, 2000 - gut.bmj.com
These guidelines were compiled by a multidisciplinary group at the request of the chairman
of the British Society of Gastroenterology's Clinical Services Committee. The prime targets …

Role of loperamide and placebo in management of irritable bowel syndrome (IBS)

PA Cann, NW Read, CD Holdsworth… - Digestive diseases and …, 1984 - Springer
Symptom scores, stool data, and the transit of a standard, solid meal were measured in 28
patients with irritable bowel syndrome (IBS) during baseline conditions and after five weeks …

The development of a spacer layer imaging method (SLIM) for mapping elastohydrodynamic contacts

PM Cann, HA Spikes, J Hutchinson - Tribology Transactions, 1996 - Taylor & Francis
Optical interferometry has proved to be a valuable experimental tool in the study of
elastohydrodynamic lubrication (EHD). It is a technique that gives detailed information on …

Film thickness in starved EHL point contacts

F Chevalier, AA Lubrecht, PME Cann, F Colin… - 1998 - asmedigitalcollection.asme.org
This paper presents a numerical study of the effects of inlet supply starvation on film
thickness in EHL point contacts. Generally this problem is treated using the position of the …

Effect of coffee on distal colon function.

SR Brown, PA Cann, NW Read - Gut, 1990 - gut.bmj.com
Ninety nine healthy young volunteers (58 men, 34 women, aged 17-27 years) answered a
questionnaire concerning their bowel habit with particular reference to the effects of …

The transition between fully flooded and starved regimes in EHL

PME Cann, B Damiens, AA Lubrecht - Tribology International, 2004 - Elsevier
Lubricant starvation of the contact can occur in high-speed oil or grease lubricated bearings
resulting in reduced elastohydrodynamic (EHL) film thickness (Lubricat. Sci. 11 (1999) 227) …