User profiles for "author:P J O'Dwyer"
Patrick Joseph O' DwyerProfessor University of Glasgow Verified email at clinmed.gla.ac.uk Cited by 17233 |
Inguinal hernias
JT Jenkins, PJ O'dwyer - Bmj, 2008 - bmj.com
Abdominal wall hernias are common, with a prevalence of 1.7% for all ages and 4% for
those aged over 45 years. Inguinal hernias account for 75% of abdominal wall hernias, with …
those aged over 45 years. Inguinal hernias account for 75% of abdominal wall hernias, with …
Bile duct injury and bile leakage in laparoscopic cholecystectomy
AJ McMahon, G Fullarton, JN Baxter… - Journal of British …, 1995 - academic.oup.com
The introduction of laparoscopic cholecystectomy has been associated with an increased
incidence of bile duct injury. This review presents the incidence of bile duct injury in reported …
incidence of bile duct injury. This review presents the incidence of bile duct injury in reported …
The NCI-MATCH trial: lessons for precision oncology
Abstract The NCI-MATCH (Molecular Analysis for Therapy Choice) trial (NCT02465060) was
launched in 2015 as a genomically driven, signal-seeking precision medicine platform trial …
launched in 2015 as a genomically driven, signal-seeking precision medicine platform trial …
[HTML][HTML] Inhibition of mutated, activated BRAF in metastatic melanoma
Background The identification of somatic mutations in the gene encoding the serine–
threonine protein kinase B-RAF (BRAF) in the majority of melanomas offers an opportunity to …
threonine protein kinase B-RAF (BRAF) in the majority of melanomas offers an opportunity to …
[PDF][PDF] Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern …
BJ Giantonio, PJ Catalano, NJ Meropol… - Journal of clinical …, 2007 - Citeseer
Purpose Colorectal cancer is the second leading cause of cancer mortality in the United
States. Antiangiogenic therapy with bevacizumab combined with chemotherapy improves …
States. Antiangiogenic therapy with bevacizumab combined with chemotherapy improves …
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
GL Beatty, EG Chiorean, MP Fishman, B Saboury… - Science, 2011 - science.org
Immunosuppressive tumor microenvironments can restrain antitumor immunity, particularly
in pancreatic ductal adenocarcinoma (PDA). Because CD40 activation can reverse immune …
in pancreatic ductal adenocarcinoma (PDA). Because CD40 activation can reverse immune …
[HTML][HTML] Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy
The poor clinical outcome in pancreatic ductal adenocarcinoma (PDA) is attributed to
intrinsic chemoresistance and a growth-permissive tumor microenvironment. Conversion of …
intrinsic chemoresistance and a growth-permissive tumor microenvironment. Conversion of …
[PDF][PDF] Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
MJ Ratain, TIM Eisen, WM Stadler… - Journal of Clinical …, 2006 - biostat.wisc.edu
Phase II Placebo-Controlled Randomized Discontinuation Trial of Sorafenib in Patients With
Metastatic Renal Cell Carcinoma Page 1 Phase II Placebo-Controlled Randomized …
Metastatic Renal Cell Carcinoma Page 1 Phase II Placebo-Controlled Randomized …
[HTML][HTML] Phase II pilot study of vemurafenib in patients with metastatic BRAF-mutated colorectal cancer
Purpose BRAF V600E mutation is seen in 5% to 8% of patients with metastatic colorectal
cancer (CRC) and is associated with poor prognosis. Vemurafenib, an oral BRAF V600 …
cancer (CRC) and is associated with poor prognosis. Vemurafenib, an oral BRAF V600 …
High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.
AK Godwin, A Meister, PJ O'Dwyer… - Proceedings of the …, 1992 - National Acad Sciences
Exposure of human ovarian tumor cell lines to cisplatin led to development of cell lines that
exhibited increasing degrees of drug resistance, which were closely correlated with increase …
exhibited increasing degrees of drug resistance, which were closely correlated with increase …