Histocompatibility antigens associated with adult coeliac disease

PL Stokes, GKT Holmes, P Asquith, P Mackintosh… - The Lancet, 1972 - Elsevier
The histocompatibility (HL-A) antigen phenotype of 49 patients with adult coeliac disease
(ACD) was studied; HL-A1 occurred in 78% and HL-A8 in 88% of ACD patients, compared …

Coeliac disease, gluten-free diet, and malignancy.

GK Holmes, PL Stokes, TM Sorahan, P Prior… - Gut, 1976 - gut.bmj.com
Two hundred and two patients with coeliac disease or idiopathic steatorrhoea previously
reported from this unit have been reviewed after a further 10 years of follow-up. Of 20 more …

Familial aspects of coeliac disease

PL Stokes, R Ferguson, GKT Holmes… - QJM: An International …, 1976 - academic.oup.com
The incidence of coeliac disease amongst first-degree relatives of 115 patients with coeliac
disease aged between nine and 75 years has been studied. Of 689 relatives 526 were living …

Folate metabolism in scurvy.

PL Stokes, V Melikian, RL Leeming… - 1975 - cabidigitallibrary.org
In a man 64 years old with scurvy and megaloblastic anaemia the main folacin derivative in
urine was 10-formyl folic acid. After treatment with ascorbic acid the main metabolite was 5 …

Cellular infiltrate of jejunal biopsies in adult coeliac disease in relation to gluten withdrawal

GKT Holmes, P Asquith, PL Stokes, WT Cooke - Gut, 1974 - gut.bmj.com
A comparison has been made of inflammatory cell counts in the lamina propria and
epithelium of jejunal biopsies in 11 patients with adult coeliac disease with those found in 12 …

Histocompatibility antigens in patients with inflammatory-bowel disease

P Asquith, PL Stokes, P Mackintosh, GKT Holmes… - The Lancet, 1974 - Elsevier
The histocompatibility (HL-A) antigen phenotypes of 48 patients with ulcerative colitis (uc)
and 56 patients with Crohn's disease (CD) were studied. In UC there was a significantly …

Inheritance and influence of histocompatibility (HL-A) antigens in adult coeliac disease

PL Stokes, P Asquith, GKT Holmes, P Mackintosh… - Gut, 1973 - gut.bmj.com
In a study of histocompatibility antigens in adult coeliac disease the HL-A phenotypes have
been determined in 117 patients and 149 of their first-degree relatives, of whom 94 had had …

Malignancy in relatives of patients with coeliac disease.

PL Stokes, P Prior, TM Sorahan… - … of Epidemiology & …, 1976 - jech.bmj.com
A survey of 1329 relatives of 139 patients with coeliac disease demonstrated an overall
increase of cancer deaths particularly in women, but this did not quite reach 5 percent …

Genetics of coeliac disease

PL Stokes, P Asquith, WT Cooke - Clinics in Gastroenterology, 1973 - Elsevier
In conclusion we have obtained confirmation of the familial nature of coeliac disease using
adult patients as propositi. The 18· 3 per cent frequency of coeliac disease in first-degree …

Malignancy

PL Stokes, GKT Holmes - Clinics in gastroenterology, 1974 - Elsevier
An association between steatorrhoea and malignant lymphoid tumours of the
gastrointestinal tract has been recognised since reports by Golden in 1936 and Fairley and …