Introduction Durability is a key requirement for the broad acceptance of bariatric surgery. We
report on durability at and beyond 10 years with a systematic review and meta-analysis of all …

This publication describes uniform definitions for cardiovascular and stroke outcomes
developed by the Standardized Data Collection for Cardiovascular Trials Initiative and the …

This article is the first in a series of seven that will provide an overview of central concepts
and topical issues in modern genetic epidemiology. In this article, we provide an overall …

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of
Complex Diseases of Middle and Old Age | PLOS Medicine Skip to main content …

Blood pressure is a heritable trait influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥ 140 mm …

Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the
diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 …

Background—Heart failure has an annual mortality rate ranging from 5% to 75%. The
purpose of the study was to develop and validate a multivariate risk model to predict 1-, 2 …

Background Acute coronary syndromes arise from coronary atherosclerosis with
superimposed thrombosis. Since factor Xa plays a central role in thrombosis, the inhibition of …

Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …

Although forest edges have been studied extensively as an important consequence of
fragmentation, a unifying theory of edge influence has yet to be developed. Our objective …