[HTML][HTML] Irritable bowel syndrome: a disease still searching for pathogenesis, diagnosis and therapy

M Bellini, D Gambaccini, C Stasi… - World journal of …, 2014 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is the most frequently diagnosed functional gastrointestinal
disorder in primary and secondary care. It is characterised by abdominal discomfort, pain …

[HTML][HTML] Gastroparesis: new insights into an old disease

P Usai-Satta, M Bellini, O Morelli, F Geri… - World Journal of …, 2020 - ncbi.nlm.nih.gov
Gastroparesis (Gp) is a chronic disease characterized by a delayed gastric emptying in the
absence of mechanical obstruction. Although this condition has been reported in the …

Chronic idiopathic constipation in adults: a review on current guidelines and emerging treatment options

G Bassotti, P Usai Satta, M Bellini - Clinical and Experimental …, 2021 - Taylor & Francis
Chronic idiopathic constipation (CIC) is a common functional bowel disorder characterized
by difficult, infrequent, and/or incomplete defecation. It has a great impact on the quality of …

Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome

M Henström, L Diekmann, F Bonfiglio, F Hadizadeh… - Gut, 2018 - gut.bmj.com
Objective IBS is a common gut disorder of uncertain pathogenesis. Among other factors,
genetics and certain foods are proposed to contribute. Congenital sucrase–isomaltase …

Loss-of-function of the voltage-gated sodium channel NaV1. 5 (channelopathies) in patients with irritable bowel syndrome

A Beyder, A Mazzone, PR Strege, DJ Tester, YA Saito… - Gastroenterology, 2014 - Elsevier
Background & Aims SCN5A encodes the α-subunit of the voltage-gated sodium channel Na
V 1.5. Many patients with cardiac arrhythmias caused by mutations in SCN5A also have …

[HTML][HTML] Lactose malabsorption and intolerance: what should be the best clinical management?

P Usai-Satta, M Scarpa, F Oppia… - World journal of …, 2012 - ncbi.nlm.nih.gov
Lactose malabsorption (LM) is the incomplete hydrolysis of lactose due to lactase deficiency,
which may occur as a primary disorder or secondary to other intestinal diseases. Primary …

Female-specific association between variants on chromosome 9 and self-reported diagnosis of irritable bowel syndrome

F Bonfiglio, T Zheng, K Garcia-Etxebarria, F Hadizadeh… - Gastroenterology, 2018 - Elsevier
Background & Aims Genetic factors are believed to affect risk for irritable bowel syndrome
(IBS), but there have been no sufficiently powered and adequately sized studies. To identify …

Increased prevalence of rare sucrase-isomaltase pathogenic variants in irritable bowel syndrome patients

K Garcia-Etxebarria, T Zheng, F Bonfiglio… - Clinical …, 2018 - cghjournal.org
Patients with irritable bowel syndrome (IBS) often associate their symptoms to certain foods.
In congenital sucrase-isomaltase deficiency (CSID), recessive mutations in the SI gene …

[HTML][HTML] Chronic constipation diagnosis and treatment evaluation: the “CHRO. CO. DI. TE” study

M Bellini, P Usai-Satta, A Bove, R Bocchini… - BMC …, 2017 - Springer
Abstract Background According to Rome criteria, chronic constipation (CC) includes
functional constipation (FC) and irritable bowel syndrome with constipation (IBS-C). Some …

[HTML][HTML] Chronic autoimmune disorders are increased in coeliac disease: a case–control study

S Bibbò, GM Pes, P Usai-Satta, R Salis, S Soro… - Medicine, 2017 - journals.lww.com
Chronic autoimmune disorders are increased in coeliac diseas... : Medicine Chronic autoimmune
disorders are increased in coeliac disease: A case–control study : Medicine Log in or Register …