Context: Circulating levels of 25-hydroxyvitamin D [25 (OH) D] may affect the prognosis of
cancer patients; however, the epidemiological results are not consistent. Objective: To …

Background Nirmatrelvir–ritonavir has been authorized for emergency use by many
countries for the treatment of coronavirus disease 2019 (Covid-19). However, the supply …

Objective Hepatocellular carcinoma (HCC) is an aggressive malignancy with limited
effective treatment options. An alternative strategy is to target cells, such as tumour …

Osteosarcoma is the most frequent primary bone tumor with poor prognosis. Through RNA-
sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic …

Vitamin D and calcium intake have been suggested to have protective effects against breast
cancer; however, the data have been inconclusive. The present meta-analysis examined the …

Individuals with gallbladder carcinoma (GBC), the most aggressive malignancy of the biliary
tract, have a poor prognosis. Here we report the identification of somatic mutations for GBC …

Background: Environmental cadmium, with a high average dietary intake, is a severe public
health risk. However, the long-term health implications of environmental exposure to …

Gut microbiota dysbiosis plays an important role in the progression of non-alcoholic fatty
liver disease (NAFLD), and no approved drugs are available for NAFLD treatment. In this …

Although hepatitis B virus (HBV) infection is the leading cause of liver fibrosis (LF), the
mechanisms underlying liver fibrotic progression remain unclear. Here, we investigated the …

Experimental data suggest a protective effect of vitamin D on breast cancer; however,
epidemiologic results remain inclusive. With a Chinese population-based case-control study …