User profiles for "author:Phillip A Engen"
Phillip A. Engen, MSLaboratory Research Supervisor, Rush University Medical Center Verified email at rush.edu Cited by 10642 |
[HTML][HTML] The gastrointestinal microbiome: alcohol effects on the composition of intestinal microbiota
The excessive use of alcohol is a global problem causing many adverse pathological health
effects and a significant financial health care burden. This review addresses the effect of …
effects and a significant financial health care burden. This review addresses the effect of …
[HTML][HTML] Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's …
Recent evidence provides support for involvement of the microbiota-gut-brain axis in
Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory intestinal …
Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory intestinal …
[HTML][HTML] Diet in Parkinson's disease: critical role for the microbiome
A Jackson, CB Forsyth, M Shaikh, RM Voigt… - Frontiers in …, 2019 - frontiersin.org
Background: Parkinson's disease (PD) is the most common movement disorder affecting up
to 1% of the population above the age of 60 and 4–5% of those above the age of 85. Little …
to 1% of the population above the age of 60 and 4–5% of those above the age of 85. Little …
Colonic bacterial composition in Parkinson's disease
Abstract Introduction We showed that Parkinson's disease (PD) patients have alpha‐
synuclein (α‐Syn) aggregation in their colon with evidence of colonic inflammation. If PD …
synuclein (α‐Syn) aggregation in their colon with evidence of colonic inflammation. If PD …
Colonic microbiome is altered in alcoholism
EA Mutlu, PM Gillevet, H Rangwala… - American Journal …, 2012 - journals.physiology.org
Several studies indicate the importance of colonic microbiota in metabolic and inflammatory
disorders and importance of diet on microbiota composition. The effects of alcohol, one of …
disorders and importance of diet on microbiota composition. The effects of alcohol, one of …
Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice
Objective Recent evidence suggesting an important role of gut-derived inflammation in brain
disorders has opened up new directions to explore the possible role of the gut-brain axis in …
disorders has opened up new directions to explore the possible role of the gut-brain axis in …
Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome
Recent studies suggest an association between particulate matter (PM) air pollution and
gastrointestinal (GI) disease. In addition to direct deposition, PM can be indirectly deposited …
gastrointestinal (GI) disease. In addition to direct deposition, PM can be indirectly deposited …
[HTML][HTML] Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice
EA Mutlu, PA Engen, S Soberanes, D Urich… - Particle and fibre …, 2011 - Springer
Background Exposure to particulate matter (PM) air pollution may be an important
environmental factor leading to exacerbations of inflammatory illnesses in the GI tract. PM …
environmental factor leading to exacerbations of inflammatory illnesses in the GI tract. PM …
[HTML][HTML] Dietary fiber treatment corrects the composition of gut microbiota, promotes SCFA production, and suppresses colon carcinogenesis
Epidemiological studies propose a protective role for dietary fiber in colon cancer (CRC).
One possible mechanism of fiber is its fermentation property in the gut and ability to change …
One possible mechanism of fiber is its fermentation property in the gut and ability to change …
[HTML][HTML] Lower neighborhood socioeconomic status associated with reduced diversity of the colonic microbiota in healthy adults
In the United States, there are persistent and widening socioeconomic gaps in morbidity and
mortality from chronic diseases. Although most disparities research focuses on person-level …
mortality from chronic diseases. Although most disparities research focuses on person-level …