Updated international consensus diagnostic criteria for eosinophilic esophagitis: proceedings of the AGREE conference

ES Dellon, CA Liacouras, J Molina-Infante, GT Furuta… - Gastroenterology, 2018 - Elsevier
Background & Aims Over the last decade, clinical experiences and research studies raised
concerns regarding use of proton pump inhibitors (PPIs) as part of the diagnostic strategy for …

American Gastroenterological Association technical review on the management of Barrett's esophagus

SJ Spechler, P Sharma, RF Souza, JM Inadomi… - …, 2011 - gastrojournal.org
The aim of evidence-based medicine is to improve the quality of health care by integrating
the best research evidence with clinical expertise and patient values. Evidence-based …

Barrett's esophagus

SJ Spechler, RF Souza - New England Journal of Medicine, 2014 - Mass Medical Soc
Barrett's Esophagus | NEJM Skip to main content NEJM Group Follow Us Facebook Twitter
Instagram YouTube LinkedIn Prepare to become a physician, build your knowledge, lead a …

[HTML][HTML] Radiofrequency ablation in Barrett's esophagus with dysplasia

NJ Shaheen, P Sharma, BF Overholt… - … England Journal of …, 2009 - Mass Medical Soc
Background Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is
associated with an increased risk of esophageal adenocarcinoma. We assessed whether …

Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins

RD Ramirez, S Sheridan, L Girard, M Sato, Y Kim… - Cancer research, 2004 - AACR
By expressing two genes (hTERT and Cdk4), we have developed a method to reproducibly
generate continuously replicating human bronchial epithelial cell (HBEC) lines that provide …

Durability of radiofrequency ablation in Barrett's esophagus with dysplasia

NJ Shaheen, BF Overholt, RE Sampliner, HC Wolfsen… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Radiofrequency ablation (RFA) can eradicate dysplasia and
intestinal metaplasia in patients with dysplastic Barrett's esophagus (BE), and reduce rates …

Gastroesophageal reflux might cause esophagitis through a cytokine-mediated mechanism rather than caustic acid injury

RF Souza, X Huo, V Mittal, CM Schuler, SW Carmack… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Reflux esophagitis is believed to be caused by the caustic effects of
refluxed gastric acid on esophageal epithelial cells. However, caustic chemical injuries …

Diagnosis and management of Barrett's esophagus: an updated ACG guideline

NJ Shaheen, GW Falk, PG Iyer, RF Souza… - Official journal of the …, 2022 - journals.lww.com
Barrett's esophagus (BE) is a common condition associated with chronic gastroesophageal
reflux disease. BE is the only known precursor to esophageal adenocarcinoma, a highly …

Thoughts on the complex relationship between gastroesophageal reflux disease and eosinophilic esophagitis

SJ Spechler, RM Genta, RF Souza - Official journal of the …, 2007 - journals.lww.com
Recent data suggest that the interaction between gastroesophageal reflux disease (GERD)
and eosinophilic esophagitis can be complex, and that the notion of establishing a clear …

Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells

RF Souza, K Shewmake, DG Beer, B Cryer… - Cancer Research, 2000 - AACR
Adenocarcinoma in Barrett's esophagus has been increasing in incidence at a rapid rate for
more than two decades. Cyclooxygenase (COX)-2 appears to play an important role in …